What we can learn from open-label extensions of randomized clinical trials

被引:10
作者
Cummings, JL [1 ]
机构
[1] Univ Calif Los Angeles, Reed Neurol Res Ctr, David Geffen Sch Med, Los Angeles, CA 90024 USA
关键词
D O I
10.1001/archneur.63.1.18
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
引用
收藏
页码:18 / 19
页数:2
相关论文
共 10 条
[1]   Management of patients with Alzheimer's disease plus cerebrovascular disease: 12-month treatment with galantamine [J].
Bullock, R ;
Erkinjuntti, T ;
Lilienfeld, S .
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, 2004, 17 (1-2) :29-34
[2]   A 52-week study of the efficacy of rivastigmine in patients with mild to moderately severe Alzheimer's disease [J].
Farlow, M ;
Anand, R ;
Messina, J ;
Hartman, R ;
Veach, J .
EUROPEAN NEUROLOGY, 2000, 44 (04) :236-241
[3]  
LEBER P, 1997, ALZHEIMER DIS ASS S5, V11, P10
[4]   Long-term outcomes of galantamine treatment in patients with Alzheimer disease [J].
Lyketsos, CG ;
Reichman, WE ;
Kershaw, P ;
Zhu, Y .
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY, 2004, 12 (05) :473-482
[5]   A 24-week open-label extension study of memantine in moderate to severe Alzheimer disease [J].
Reisberg, B ;
Doody, R ;
Stöffler, A ;
Schmitt, F ;
Ferris, S ;
Möbius, HJ .
ARCHIVES OF NEUROLOGY, 2006, 63 (01) :49-54
[6]   Memantine in moderate-to-severe Alzheimer's disease [J].
Reisberg, B ;
Doody, R ;
Stoffler, A ;
Schmitt, F ;
Ferris, S ;
Mobius, HJ .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (14) :1333-1341
[7]   Long-term efficacy and safety of donepezil in the treatment of Alzheimer's disease: final analysis of a US multicentre open-label study [J].
Rogers, SL ;
Doody, RS ;
Pratt, RD ;
Ieni, JR .
EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2000, 10 (03) :195-203
[8]   Relationship of disease severity to decline on specific cognitive and functional measures in Alzheimer disease [J].
Schmeidler, J ;
Mohs, RC ;
Aryan, M .
ALZHEIMER DISEASE & ASSOCIATED DISORDERS, 1998, 12 (03) :146-151
[9]  
STERN RG, 1994, AM J PSYCHIAT, V151, P390
[10]   Clinical trial designs for demonstrating disease-course-altering effects in dementia [J].
Whitehouse, PJ ;
Kittner, B ;
Roessner, M ;
Rossor, M ;
Sano, M ;
Thal, G ;
Winblad, B .
ALZHEIMER DISEASE & ASSOCIATED DISORDERS, 1998, 12 (04) :281-294