CD4/CD8 Double-negative Mycosis Fungoides: A Case Report and Literature Review

被引：17

作者：

Ito, Ayako ^{[1
]}

Sugita, Kazunari ^{[1
]}

Ikeda, Ayano ^{[1
]}

Yamamoto, Osamu ^{[1
]}

机构：

[1] Tottori Univ, Fac Med, Sch Med, Div Dermatol,Dept Med Sensory & Motor Organs, Yonago, Tottori 6838503, Japan

来源：

YONAGO ACTA MEDICA | 2019年 / 62卷 / 01期

关键词：

CD4/CD8; double-negative; hypopigmented; mycosis fungoides; T-CELL LYMPHOMA; SEZARY-SYNDROME; EUROPEAN-ORGANIZATION; CUTANEOUS-LYMPHOMAS; INTERFERON-GAMMA; PLAQUE-STAGE; TASK-FORCE; CLASSIFICATION; EXPRESSION; PROGNOSIS;

D O I：

10.33160/yam.2019.03.021

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Mycosis fungoides, the most common subtype of cutaneous T-cell lymphoma, displays a broad spectrum of clinical, histological and phenotypic variants with different prognostic impacts. The classic immunophenotype is CD3+/CD4+/CD45RO+memory T cells. CD4/CD8 double-negative mycosis fungoides is rare. Here we describe the clinicopathological features of CD4/CD8 double-negative mycosis fungoides in a 55-year-old female with a review of the literature. Although the CD4/CD8 double-negative phenotype appears to be associated with an unusual clinical presentation, it does not appear to confer prognostic significance.

引用

页码：153 / 158

页数：6

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