Outbreak of enterovirus D68 of the new B3 lineage in Stockholm, Sweden, August to September 2016

被引：63

作者：

Dyrdak, R. ^{[1
,2
]}

Grabbe, M. ^{[1
,2
]}

Hammas, B. ^{[1
,2
]}

Ekwall, J. ^{[3
]}

Hansson, K. E. ^{[4
]}

Luthander, J. ^{[5
,6
]}

Naucler, P. ^{[7
,8
]}

Reinius, H. ^{[9
,10
]}

Rotzen-Ostlund, M. ^{[1
]}

Albert, J. ^{[1
,2
]}

机构：

[1] Karolinska Univ Hosp, Dept Clin Microbiol, Stockholm, Sweden

[2] Karolinska Inst, Dept Microbiol Tumor & Cell Biol, Stockholm, Sweden

[3] Karolinska Univ Hosp, Astrid Lindgren Childrens Hosp, Stockholm, Sweden

[4] Soder Sjukhuset, Dept Infect Dis, Stockholm, Sweden

[5] Karolinska Univ Hosp, Astrid Lindgren Childrens Hosp, Pediat Infect Dis Unit, Stockholm, Sweden

[6] Karolinska Inst, Dept Womens & Childrens Hlth, Stockholm, Sweden

[7] Karolinska Inst, Dept Med Solna, Infect Dis Unit, Stockholm, Sweden

[8] Karolinska Univ Hosp, Dept Infect Dis, Stockholm, Sweden

[9] Akad Univ Hosp, Dept Anesthesiol & Intens Care, Uppsala, Sweden

[10] Uppsala Univ, Dept Surg Sci, Uppsala, Sweden

来源：

EUROSURVEILLANCE | 2016年 / 21卷 / 46期

关键词：

D O I：

10.2807/1560-7917.ES.2016.21.46.30403

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We report an enterovirus D68 ( EV-D68) outbreak in Stockholm Sweden in 2016. Between 22 August and 25 September EV-D68 was detected in 74/ 495 respiratory samples analysed at the Karolinska University Hospital. During the peak week, 30/ 91 ( 33%) samples were EV-D68 positive. Viral protein ( VP) P4/ VP2 sequencing revealed that cases were caused by B3 lineage strains. Forty-four ( 59%) EV-D68-positive patients were children aged = 5 years. Ten patients had severe respiratory or neurological symptoms and one died. We report an outbreak of enterovirus D68 ( EV-D68) infections in Stockholm, Sweden in late August and September of 2016 caused by the newly described B3 lineage [1].

引用

页码：5 / 10

页数：6

共 12 条

[1] Coexistence of two clades of enterovirus D68 in pediatric Swedish patients in the summer and fall of 2014 [J].

Dyrdak, Robert ;

Rotzen-Ostlund, Maria ;

Samuelson, Agneta ;

Eriksson, Margareta ;

Albert, Jan .

INFECTIOUS DISEASES, 2015, 47 (10) :734-738

[2]

European Centre for Disease Prevention and Control, 2016, RAPID RISK ASSESSMEN

[3]

European Centre for Disease Prevention and Control (ECDC), 2014, ENT D68 DET US

[4] Molecular evolution and the global reemergence of enterovirus D68 by genome-wide analysis [J].

Gong, Yu-Nong ;

Yang, Shu-Li ;

Shih, Shin-Ru ;

Huang, Yhu-Chering ;

Chang, Pi-Yueh ;

Huang, Chung-Guei ;

Kao, Kuo-Chin ;

Hu, Han-Chung ;

Liu, Yi-Chun ;

Tsao, Kuo-Chien .

MEDICINE, 2016, 95 (31)

[5] Global emergence of enterovirus D68: a systematic review [J].

Holm-Hansen, Charlotte Carina ;

Midgley, Sofie Elisabeth ;

Fischer, Thea Kolsen .

LANCET INFECTIOUS DISEASES, 2016, 16 (05) :E64-E75

[6] Upsurge of Enterovirus D68, the Netherlands, 2016 [J].

Knoester, Marjolein ;

Scholvinck, Elisabeth H. ;

Poelman, Randy ;

Smit, Sylvia ;

Vermont, Clementien L. ;

Niesters, Hubert G. M. ;

Van Leer-Buter, Coretta C. .

EMERGING INFECTIOUS DISEASES, 2017, 23 (01) :140-143

[7]

Midgley Claire M, 2014, MMWR Morb Mortal Wkly Rep, V63, P798

[8]

Pastula DM, 2014, MMWR-MORBID MORTAL W, V63, P901

[9] A New Real-Time Reverse Transcription-PCR Assay for Detection of Human Enterovirus 68 in Respiratory Samples [J].

Piralla, Antonio ;

Girello, Alessia ;

Premoli, Marta ;

Baldanti, Fausto .

JOURNAL OF CLINICAL MICROBIOLOGY, 2015, 53 (05) :1725-1726

[10] Performance of the Simplexa™ Flu A/B & RSV Direct Kit on respiratory samples collected in saline solution [J].

Svensson, Malin J. ;

Lind, Ingrid ;

Wirgart, Benita Zweygberg ;

Ostlund, Maria Rotzen ;

Albert, Jan .

SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES, 2014, 46 (12) :825-831

← 1 2 →