Recent Advances on Marine Alkaloids from Sponges

被引：38
作者：
Bian, Changhao [1 ]
Wang, Jiangming [1 ]
Zhou, Xinyi [1 ]
Wu, Wenhui [1 ,2 ,3 ]
Guo, Ruihua [1 ,2 ,3 ]
机构：
[1] Shanghai Ocean Univ, Coll Food Sci & Technol, Shanghai 201306, Peoples R China
[2] Shanghai Engn Res Ctr Aquat Prod Proc & Preservat, Shanghai 201306, Peoples R China
[3] Minist Agr, Lab Qual & Safety Risk Assessment Aquat Prod Stor, Shanghai 201306, Peoples R China
来源：
CHEMISTRY & BIODIVERSITY | 2020年 / 17卷 / 10期
基金：
中国国家自然科学基金;
关键词：
alkaloids; sponges; biological activity; indole alkaloids; carboline alkaloids; PYRROLE-IMIDAZOLE ALKALOIDS; PENTACYCLIC GUANIDINE ALKALOIDS; BETA-CARBOLINE ALKALOIDS; BROMOTYROSINE ALKALOIDS; INDONESIAN SPONGE; INDOLE-ALKALOIDS; BROMOPYRROLE ALKALOIDS; MANZAMINE ALKALOIDS; DITERPENE ALKALOIDS; NATURAL-PRODUCTS;
D O I：
10.1002/cbdv.202000186
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Alkaloids from marine secondary metabolites have received extensive attention from pharmacists in recent years. Miscellaneous alkaloids derived from marine sponges possessed various pharmacological activities including cytotoxicity, antimicrobial, antioxidant, and so on. Herein, we summarized 149 marine alkaloids from sponges based on their structures and bioactivities reported from 2015 to 2020 and analyzed the production environment of marine sponges with rich alkaloids. Moreover, we discussed biosynthesis routes of pyrrole and guanidine alkaloids from marine spongesAgelasandMonanchora. This article will be beneficial for future research on drugs from marine natural products.
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页数：28
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