Academic, Phase I/II Trial on T Cells Expressing a Second Generation, CD19-Specific Chimeric Antigen Receptor (CAR) and Inducible Caspase 9 Safety Switch for the Treatment of B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) and B-Cell Non-Hodgkin Lymphoma (B-NHL) in Children

被引：4

作者：

Del Bufalo, Francesca ^{[1
]}

Quintarelli, Concetta ^{[2
]}

De Angelis, Biagio ^{[3
]}

Caruana, Ignazio ^{[4
]}

Sinibaldi, Matilde ^{[3
]}

Vinti, Luciana ^{[1
]}

Merli, Pietro ^{[1
]}

Algeri, Mattia ^{[5
]}

Ruggeri, Annalisa ^{[1
]}

Galaverna, Federica ^{[1
]}

Cirillo, Valentina ^{[1
]}

Cefalo, Maria Giuseppina ^{[1
]}

Pira, Giuseppina Li ^{[1
]}

Leone, Giovanna ^{[6
]}

Bertaina, Valentina ^{[1
]}

Fassio, Franca ^{[7
]}

Gunetti, Monica ^{[7
]}

Iacovelli, Stefano ^{[8
]}

Locatelli, Franco ^{[1
,9
]}

机构：

[1] IRCCS Bambino Gesu Childrens Hosp, Dept Pediat Hematol Oncol Cell & Gene Therapy, Rome, Italy

[2] Bambino Gesu Pediat Hosp, Dept Oncohaematol & Cell & Gene Therapy, Rome, Italy

[3] IRCCS Bambino Gesu Childrens Hosp, Dept Hematol Oncol & Cell & Gene Therapy, Rome, Italy

[4] Bambino Gesu Pediat Hosp, Dept Pediat Hematol & Oncol & Cell & Gene Therapy, Rome, Italy

[5] Bambino Gesu Pediat Hosp, Dept Pediat Hematol Oncol Cell & Gene Therapy, Rome, Italy

[6] IRCCS Bambino Gesu Childrens Hosp, Dept Labs, Immunohematol & Transfus Med Unit, Rome, Italy

[7] Bambino Gesu Pediat Hosp, Officina Farmaceut, GMP Facil, IRCCS, Rome, Italy

[8] Bambino Gesu Pediat Hosp, Officina Farmaceut, GMP Facil, Rome, Italy

[9] Univ Rome Sapienza, Rome, Italy

来源：

关键词：

D O I：

10.1182/blood-2019-129821

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

1341

引用

页数：4