Analysis of the cercosporin polyketide synthase CTB1 reveals a new fungal thioesterase function

被引：31

作者：

Newman, Adam G. ^{[1
]}

Vagstad, Anna L. ^{[1
]}

Belecki, Katherine ^{[1
]}

Scheerer, Jonathan R. ^{[2
]}

Townsend, Craig A. ^{[1
]}

机构：

[1] Johns Hopkins Univ, Dept Chem, Baltimore, MD 21218 USA

[2] Coll William & Mary, Dept Chem, Williamsburg, VA 23187 USA

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 96期

关键词：

PHOTOSENSITIZING TOXIN; PRODUCT; IDENTIFICATION; BIOSYNTHESIS; PREDICTION; CLEAVAGE; DOMAIN;

D O I：

10.1039/c2cc36010a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The polyketide synthase CTB1 is demonstrated to catalyze pyrone formation thereby expanding the known biosynthetic repertoire of thioesterase domains in iterative, non-reducing polyketide synthases.

引用

页码：11772 / 11774

页数：3

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