Synthesis of quinolactacide via an acyl migration reaction and dehydrogenation with manganese dioxide, and its insecticidal activities

被引：22

作者：

Abe, M ^{[1
]}

Imai, T ^{[1
]}

Ishii, N ^{[1
]}

Usui, M ^{[1
]}

机构：

[1] Otsuka Chem Co Ltd, Naruto Res Ctr, Naruto, Tokushima 7728601, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2006年 / 70卷 / 01期

关键词：

quinolactacide; insecticidal activity; acyl migration reaction; dehydrogenation;

D O I：

10.1271/bbb.70.303

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Quinolactacide isolated from Penicillium citrinum F 1539 was synthesized and evaluated for its insecticidal activities. The key steps of the total synthesis were an acyl migration reaction of the enol ester intermediate and dehydrogenation of tetrahydroquinolactacide with manganese dioxide. The synthesized quinolactacide showed 100% and 42% mortality against the green peach aphid (Myzus persicae) and diamondback moth (Plutella xylostella) at 500 ppm, respectively.

引用

页码：303 / 306

页数：4

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