Signalling pathways in two-component phosphorelay systems

被引:116
|
作者
Perraud, AL [1 ]
Weiss, V
Gross, R
机构
[1] Univ Wurzburg, Biozentrum, Theodor Boveri Inst, Lehrstuhl Mikrobiol, D-97074 Wurzburg, Germany
[2] Univ Konstanz, Fak Biol, D-78434 Constance, Germany
关键词
D O I
10.1016/S0966-842X(99)01458-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Two-component systems are characterized by phosphotransfer reactions involving histidine and aspartate residues in highly conserved signalling domains. Although the basic principles of signal transduction by these systems have been elucidated, several important aspects, such as their integration into more complex cellular regulatory networks and the molecular basis of the specificity of signal transduction, remain unknown.
引用
收藏
页码:115 / 120
页数:6
相关论文
共 50 条
  • [41] Unusual two-component signal transduction pathways in the actinobacteria
    Hutchings, Matthew I.
    ADVANCES IN APPLIED MICROBIOLOGY, VOL 61, 2007, 61 : 1 - 26
  • [42] Temporal and evolutionary dynamics of two-component signaling pathways
    Salazar, Michael E.
    Laub, Michael T.
    CURRENT OPINION IN MICROBIOLOGY, 2015, 24 : 7 - 14
  • [43] Molecular Mechanisms of Signalling Specificity Via Phosphorelay Pathways in Arabidopsis
    Horak, Jakub
    Janda, Lubomir
    Pekarova, Blanka
    Hejatko, Jan
    CURRENT PROTEIN & PEPTIDE SCIENCE, 2011, 12 (02) : 126 - 136
  • [44] Allocation of Two Redundancies in Two-Component Series Systems
    Zhao, Peng
    Chan, Ping Shing
    Li, Long
    Ng, Hon Keung Tony
    NAVAL RESEARCH LOGISTICS, 2013, 60 (07) : 588 - 598
  • [45] Searching for Potential Drug Targets in Two-component and Phosphorelay Signal-transduction Systems using Three-dimensional Cluster Analysis
    Xiao-Hui CAI Qing ZHANG Shuo-Yong SHI Da-Fu DING Key Laboratory of Proteonmics
    Acta Biochimica et Biophysica Sinica, 2005, (05) : 293 - 302
  • [46] Searching for potential drug targets in two-component and phosphorelay signal-transduction systems using three-dimensional cluster analysis
    Cai, XH
    Zhang, Q
    Shi, SY
    Ding, DF
    ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2005, 37 (05) : 293 - 302
  • [47] The enigma of cytosolic two-component systems: a hypothesis
    Krell, Tino
    Busch, Andreas
    Lacal, Jesus
    Silva-Jimenez, Hortencia
    Ramos, Juan-Luis
    ENVIRONMENTAL MICROBIOLOGY REPORTS, 2009, 1 (03): : 171 - 176
  • [48] An overview on the two-component systems of Streptomyces coelicolor
    Jin, Shangping
    Hui, Ming
    Lu, Yinhua
    Zhao, Yawei
    WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY, 2023, 39 (03):
  • [49] Simulation modeling of structures of two-component systems
    Karpukhin, A.A.
    Mikheeva, M.A.
    Kauchuk i Rezina, 2001, (04): : 25 - 28
  • [50] On allocation of redundancies in two-component series systems
    Zhao, Peng
    Chan, Ping Shing
    Li, Long
    Hon Keung Tony Ng
    OPERATIONS RESEARCH LETTERS, 2013, 41 (06) : 690 - 693