Comparative study of structural properties of trehalose water solutions by neutron diffraction, synchrotron radiation and simulation

被引:12
作者
Cesaro, A. [3 ]
Magazu, V. [4 ]
Migliardo, F. [1 ,2 ]
Sussich, F. [3 ]
Vadala, M. [1 ,2 ]
机构
[1] Univ Messina, Dipartimento Fis, I-98166 Messina, Italy
[2] Univ Messina, INFM, I-98166 Messina, Italy
[3] Univ Trieste, Dipartimento Biochim Biofis & Chim Macromol, I-34127 Trieste, Italy
[4] Ist CNR ITAE, I-98126 Messina, Italy
关键词
Neutron diffraction; Trehalose aqueous solutions; Hydrogen bond;
D O I
10.1016/j.physb.2004.03.098
中图分类号
O469 [凝聚态物理学];
学科分类号
070205 ;
摘要
Neutron diffraction measurements combined with H/D substitution have been performed on trehalose aqueous solutions as a function of temperature and concentration by using the SANDALS diffractometer at ISIS Facility (UK). The findings point out a high capability of trehalose to strongly affect the tetrahedral hydrogen bond network of water. The neutron diffraction results are also compared with simulation and experimental data obtained by synchrotron radiation on the phospholipid bilayer membranes (DPPC)/trehalose/H2O ternary system. (C) 2004 Elsevier B.V. All rights reserved.
引用
收藏
页码:E367 / E370
页数:4
相关论文
共 11 条
  • [1] Neutron diffraction study of high density supercritical water
    Botti, A
    Bruni, F
    Ricci, MA
    Soper, AK
    [J]. JOURNAL OF CHEMICAL PHYSICS, 1998, 109 (08) : 3180 - 3184
  • [2] Anomalous cryoprotective effectiveness of trehalose:: Raman scattering evidences
    Branca, C
    Magazù, S
    Maisano, G
    Migliardo, P
    [J]. JOURNAL OF CHEMICAL PHYSICS, 1999, 111 (01) : 281 - 287
  • [3] Branca C., 1999, RECENT RES DEV PHYS, V3, P361
  • [4] Computer simulation of the cryoprotectant disaccharide α,α-trehalose in aqueous solution
    Conrad, PB
    de Pablo, JJ
    [J]. JOURNAL OF PHYSICAL CHEMISTRY A, 1999, 103 (20) : 4049 - 4055
  • [5] PRESERVATION OF MEMBRANES IN ANHYDROBIOTIC ORGANISMS - THE ROLE OF TREHALOSE
    CROWE, JH
    CROWE, LM
    CHAPMAN, D
    [J]. SCIENCE, 1984, 223 (4637) : 701 - 703
  • [6] INTERACTION OF WATER WITH ALPHA,ALPHA-TREHALOSE IN SOLUTION - MOLECULAR-DYNAMICS SIMULATION APPROACH
    DONNAMARIA, MC
    HOWARD, EI
    GRIGERA, JR
    [J]. JOURNAL OF THE CHEMICAL SOCIETY-FARADAY TRANSACTIONS, 1994, 90 (18): : 2731 - 2735
  • [7] VITRIFICATION IN PLANTS AS A NATURAL FORM OF CRYOPROTECTION
    HIRSH, AG
    [J]. CRYOBIOLOGY, 1987, 24 (03) : 214 - 228
  • [8] COMPARISON BETWEEN TUMOR-NECROSIS-FACTOR RESPONSE AND HEAT-SHOCK RESPONSE IN L929 CELLS - CELLULAR AND MOLECULAR ASPECTS
    LEE, YJ
    HOU, ZH
    CHO, JM
    CORRY, PM
    [J]. JOURNAL OF THERMAL BIOLOGY, 1992, 17 (4-5) : 241 - 249
  • [9] Soper A.K., 1992, CHEM PHYS, V97, P2
  • [10] SOPER AK, 2000, PHYSICA B, V12, P276