Supracricoid laryngectomy with cricohyoidoepiglottopexy (CHEP) in the management of laryngeal carcinoma: oncologic results. A 35-year experience

被引:22
作者
Page, C. [1 ,2 ]
Mortuaire, G. [3 ]
Mouawad, F. [3 ]
Ganry, O. [4 ]
Darras, J. [3 ]
Pasquesoone, X. [3 ]
Chevalier, D. [3 ,5 ,6 ]
机构
[1] Univ Hosp Amiens, ENT & Head & Neck Surg Dept, Amiens, France
[2] Jules Verne Univ, Sch Med, Dept Anat, Amiens, France
[3] Univ Hosp Lille, ENT & Head & Neck Surg Dept, Lille, France
[4] Univ Hosp Amiens, Dept Publ Hlth, Amiens, France
[5] Serv ORL, F-59037 Lille, France
[6] CCF Hop Claude Huriez CHU, F-59037 Lille, France
关键词
Squamous cell carcinoma; Laryngeal cancer; Glottic cancer; Supracricoid laryngectomy with cricohyoidoepiglottopexy; Partial laryngectomy; CHEP; SQUAMOUS-CELL CARCINOMA; GLOTTIC CARCINOMA; CANCER; CRICOHYOIDOPEXY; COMPLICATIONS;
D O I
10.1007/s00405-012-2300-4
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
To evaluate the long-term oncologic results of supracricoid laryngectomy with cricohyoidoepiglottopexy (CHEP) for laryngeal cancer. A 35-year retrospective study concerning 291 patients treated by supracricoid laryngectomy with CHEP for laryngeal cancer was performed. The following postoperative data were studied: recurrence rates (lymph node and laryngeal), distant metastases and second cancer. The mortality rate and overall survival were estimated by the Kaplan-Meier method. The postoperative mortality was 1.03 %. 23 patients were lost to follow-up. The 3-year survival rate was 84 % and the 5-year survival rate was 80 %. 12 patients developed distant metastasis. 31 patients developed a second cancer. The local (laryngeal) control rate was 93.94 % and the regional (cervical lymph node) control rate was 92.05 %. In multivariate analysis, the occurrence of a second non-ENT cancer and metastasis as well as margins involvement were reliable to mortality. Supracricoid laryngectomy with CHEP appears to be associated with very good long-term oncologic results and still has a place in the management of T1, T2 and selected T3 glottic cancers.
引用
收藏
页码:1927 / 1932
页数:6
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