Intermittent Fasting: A Heart Healthy Dietary Pattern?

被引:140
作者
Dong, Tiffany A. [1 ,2 ]
Sandesara, Pratik B. [2 ,3 ]
Dhindsa, Devinder S. [2 ,3 ]
Mehta, Anurag [2 ,3 ]
Arneson, Laura C. [4 ]
Dollar, Allen L. [3 ]
Taub, Pam R. [5 ]
Sperling, Laurence S. [2 ,3 ]
机构
[1] Emory Univ, Sch Med, Dept Med, Atlanta, GA USA
[2] Emory Univ, Sch Med, Emory Clin Cardiovasc Res Inst, Atlanta, GA USA
[3] Emory Univ, Sch Med, Div Cardiol, Atlanta, GA 30322 USA
[4] Northwestern Univ, Dept Med, Feinberg Sch Med, Chicago, IL 60611 USA
[5] Univ Calif San Diego, Sch Med, Div Cardiovasc Med, La Jolla, CA 92093 USA
关键词
Alternative day fast; Circadian; Diabetes; Dyslipidemia; Hypertension; Time-restricted feeding; REDUCED MEAL FREQUENCY; CALORIC RESTRICTION; CARDIOVASCULAR-DISEASE; BODY-WEIGHT; INSULIN-RESISTANCE; CIRCADIAN-RHYTHMS; OXIDATIVE STRESS; KETOGENIC DIET; RISK; IMPACT;
D O I
10.1016/j.amjmed.2020.03.030
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Dietary patterns, such as the Dietary Approaches to Stop Hypertension (DASH) and the Mediterranean diet, have been shown to improve cardiac health. Intermittent fasting is another type of popular dietary pattern that is based on timed periods of fasting. Two different regimens are alternative day fasting and time-restricted eating. Although there are no large, randomized control trials examining the relationship between intermittent fasting and cardiovascular outcomes, current human studies that suggest this diet could reduce the risk for cardiovascular disease with improvement in weight control, hypertension, dyslipidemia, and diabetes. Intermittent fasting may exert its effects through multiple pathways, including reducing oxidative stress, optimization of circadian rhythms, and ketogenesis. This review evaluates current literature regarding the potential cardiovascular benefits of intermittent fasting and proposes directions for future research. (C) 2020 Elsevier Inc. All rights reserved.
引用
收藏
页码:901 / 907
页数:7
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