Cytotoxicity of new stilbenoids from Pholidota chinensis and their spin-labeled derivatives

被引:25
作者
Wu, Bin [1 ]
Qu, Haibin [1 ]
Cheng, Yiyu [1 ]
机构
[1] Zhejiang Univ, Coll Pharmaceut Sci, Pharmaceut Informat Inst, Hangzhou 310027, Zhejiang, Peoples R China
关键词
D O I
10.1002/cbdv.200890169
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Chemical investigation of the leave and stem of Pholidota chinensis LINDL has resulted in the isolation and characterization of three new stilbenoids. Their structures were established on the basis of spectroscopic evidence. A series of spin-labeled stilbene derivatives were synthesized. All of the new compounds were tested for cytotoxicity, and the results revealed that most of the spin-labeled stilbene derivatives showed superior cytotoxicity in vitro.
引用
收藏
页码:1803 / 1810
页数:8
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