Vagal stimulation in the treatment of epilepsy

被引：6
作者：
Iriarte, J
Urrestarazu, E
Lázaro, D
Schlumberger, E
机构：
[1] Univ Navarra, Clin Univ, Serv Neurofisiol, Unidad Epilepsia, E-31080 Pamplona, Spain
[2] Univ Navarra, Clin Univ, Unidad Neurol Infantil, E-31080 Pamplona, Spain
[3] Hosp Virgen Camino, Serv Neurofisiol Clin, Pamplona, Spain
来源：
REVISTA DE NEUROLOGIA | 2002年 / 34卷 / 06期
关键词：
drug-resistant epilepsy; vagal stimulation;
D O I：
10.33588/rn.3406.2001368
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Introduction. The vagal nerve stimulation is a new technique for the treatment of drug-resistant epilepsies. Development. In 1997, it was approved in United States by the FDA to be used in adults with refractory focal epilepsies not candidates for epilepsy surgery. Its mechanism of action is unknown. The results in the controlled studies indicated a decrease of 30-50% in the seizure frequency in around 50% of the patients, Although more experience is needed to corroborate these results, it seems reasonable as a treatment for patients with difficult epilepsies, especially when the response to the antiepileptic drugs is poor or they are producing secondary effects, and the resection of the focus is not possible.
引用
收藏
页码：511 / 518
页数：8
相关论文
共 100 条
[1]   CONSIDERATIONS FOR SAFETY WITH CHRONICALLY IMPLANTED NERVE ELECTRODES [J].
AGNEW, WF ;
MCCREERY, DB .
EPILEPSIA, 1990, 31 :S27-S32
[2]   Vagus nerve stimulation for the treatment of bilateral independent temporal lobe epilepsy [J].
Alsaadi, TM ;
Laxer, KD ;
Barbaro, JM ;
Marks, WJ ;
Garcia, PA .
EPILEPSIA, 2001, 42 (07) :954-956
[3]   Vagal nerve stimulation in the treatment of epilepsy [J].
Alvarez, LA ;
Dean, P ;
Jayakar, P ;
Duchowny, M ;
Resnick, T ;
Dunoyer, C ;
Koh, S .
REVISTA DE NEUROLOGIA, 1999, 29 (04) :385-387
[4]   An institutional experience with cervical vagus nerve trunk stimulation for medically refractory epilepsy: Rationale, technique, and outcome [J].
Amar, AP ;
Heck, CN ;
Levy, ML ;
Smith, T ;
DeGiorgio, CM ;
Oviedo, S ;
Apuzzo, MLJ .
NEUROSURGERY, 1998, 43 (06) :1265-1276
[5]   Long-term multicenter experience with vagus nerve stimulation for intractable partial seizures - Results of the XE5 trial [J].
Amar, AP ;
DeGiorgio, CM ;
Tarver, WB ;
Apuzzo, MLJ .
STEREOTACTIC AND FUNCTIONAL NEUROSURGERY, 1999, 73 (1-4) :104-108
[6]   Epilepsy, vagal nerve stimulation by the NCP system mortality, and sudden, unexpected, unexplained death [J].
Annegers, JF ;
Coan, SP ;
Hauser, WA ;
Leestma, J ;
Duffell, W ;
Tarver, B .
EPILEPSIA, 1998, 39 (02) :206-212
[7]   Bradycardia and asystole with the use of vagus nerve stimulation for the treatment of epilepsy:: A rare complication of intraoperative device testing [J].
Asconapé, JJ ;
Moore, DD ;
Zipes, DP ;
Hartman, LM ;
Duffell, WH .
EPILEPSIA, 1999, 40 (10) :1452-1454
[8]   Evaluation of refractory epilepsy treated with vagus nerve stimulation for up to 5 years [J].
Ben-Menachem, E ;
Hellström, K ;
Waldton, C ;
Augustinsson, LE .
NEUROLOGY, 1999, 52 (06) :1265-1267
[9]   EFFECTS OF VAGUS NERVE-STIMULATION ON AMINO-ACIDS AND OTHER METABOLITES IN THE CSF OF PATIENTS WITH PARTIAL SEIZURES [J].
BENMENACHEM, E ;
HAMBERGER, A ;
HEDNER, T ;
HAMMOND, EJ ;
UTHMAN, BM ;
SLATER, J ;
TREIG, T ;
STEFAN, H ;
RAMSAY, RE ;
WERNICKE, JF ;
WILDER, BJ .
EPILEPSY RESEARCH, 1995, 20 (03) :221-227
[10]   VAGUS NERVE-STIMULATION FOR TREATMENT OF PARTIAL SEIZURES .1. A CONTROLLED-STUDY OF EFFECT ON SEIZURES [J].
BENMENACHEM, E ;
MANONESPAILLAT, R ;
RISTANOVIC, R ;
WILDER, BJ ;
STEFAN, H ;
MIRZA, W ;
TARVER, WB ;
WERNICKE, JF ;
AUGUSTINSSON, L ;
BAROLAT, G ;
BONGARTZ, U ;
BERGEN, D ;
BUCHOLZ, R ;
BURCHIEL, K ;
FAUGHT, E ;
GEORGE, R ;
HUFNAGEL, A ;
KUZNIECKY, R ;
LANDY, H ;
MICHAEL, J ;
NARITOKU, D ;
PENCEK, T ;
RAMSAY, RE ;
REID, S ;
RICHARDSON, D ;
ROSENFELD, W ;
ROSENWASSER, R ;
SALINSKY, M ;
SLATER, J ;
SONNEN, A ;
STRELETZ, L ;
TALALLA, A ;
TREIG, T ;
UPTON, ARM ;
UTHMAN, B ;
WEGENER, K ;
WILLIS, J .
EPILEPSIA, 1994, 35 (03) :616-626
12345678910