A convenient, eco-friendly, and efficient method for synthesis of bis(3-indolyl)methanes "on-water"

被引：16

作者：

Mallik, Asok K. ^{[1
]}

Pal, Rammohan ^{[1
]}

Guha, Chayan ^{[1
]}

Mallik, Haimanti ^{[2
]}

机构：

[1] Jadavpur Univ, Dept Chem, Kolkata 700032, India

[2] Lady Brabourne Coll, Dept Chem, Kolkata 700017, India

来源：

GREEN CHEMISTRY LETTERS AND REVIEWS | 2012年 / 5卷 / 03期

关键词：

bis(3-indolyl)methanes; synthesis; indoles; aromatic aldehydes; on-water; CATALYZED-REACTIONS; FACILE SYNTHESIS; ACID; BIS(INDOLYL)METHANES; ALCOHOLS; INDOLES; MILD; DIINDOLYLMETHANES; BACTERIUM; ALDEHYDES;

D O I：

10.1080/17518253.2011.630027

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A convenient, eco-friendly, and efficient method for synthesis of bis(3-indolyl)methanes by the reaction of indoles with various aromatic aldehydes "on-water" has been developed. The attractive features of this method are that in cases of aldehydes which are easily oxidized to acids, no external catalyst is necessary while in other cases a trace amount (ca. 5 mol%) of commercially available and inexpensive catalyst benzoic acid is sufficient to give good to excellent yield of products.

引用

页码：321 / 327

页数：7

共 35 条

[1] TRYPTOPHAN ANALOGS FORM ADDUCTS BY COOPERATIVE REACTION WITH ALDEHYDES AND ALCOHOLS OR WITH ALDEHYDES ALONE - POSSIBLE ROLE IN ETHANOL TOXICITY [J].