A direct chemiluminescence method for the determination of prulifloxacin using tris-(4,7-diphenyl-1,10-phenanthrolinedisulfonic acid) ruthenium(II)-cerium(IV) system

被引：7
作者：
Cui, Man [2 ]
Yu, Fengshan [3 ]
Chen, Fang [3 ]
Chen, Lanhua [1 ]
机构：
[1] Huaibei Coal Ind Teachers Coll, Dept Chem, Huaibei 235000, Peoples R China
[2] Anhui Univ, Sch Chem & Chem Engn, Hefei 230039, Peoples R China
[3] Huazhong Univ Sci & Technol, Dept Chem, Hubei Key Lab Bioinorgan Chem & Mat Med, Wuhan 430074, Peoples R China
来源：
ANALYTICAL LETTERS | 2008年 / 41卷 / 11期
基金：
中国国家自然科学基金;
关键词：
chemiluminescence; cerium(IV); flow-injection; prulifloxacin; tris(4,7-diphenyl-1,10-phenanthrolinedisulfonic acid) ruthenium(II);
D O I：
10.1080/00032710802208690
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A simple, rapid, injection chemiluminescence method is described for the determination of prulifloxacin, a commonly used antibiotic. A strong chemiluminescence signal was detected when a mixture of the analyte and tris-(4,7-diphenyl-1,10-phenanthrolinedisulfonic acid)ruthenium(II) was injected into cerium(IV) sulfate. The chemiluminescence signal is proportional to the concentration of prulifloxacin in the range 4.0x10(-8) -9.0x10(-6) mol L(-1). The detection limit is 1.0x10(-8) mol L(-1), and the relative standard deviation is 2.2% (n=11) for the determination of 8.0x10(-7)mol L(-1) prulifloxacin. The proposed method was successfully applied to the determination of prulifloxacin in pharmaceutical preparations in capsules, spiked serum, and urine samples.
引用
收藏
页码：2001 / 2012
页数：12
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