Rapid and visual detection of protamine based on ionic self-assembly of a water soluble perylene diimide derivative

被引：22

作者：

Cheng, He ^{[1
,2
]}

Zhao, Yiwen ^{[1
,2
]}

Xu, Huimin ^{[1
,2
]}

Hu, Yifan ^{[1
,2
]}

Zhang, Li ^{[1
,2
]}

Song, Gang ^{[3
]}

Yao, Zhiyi ^{[1
,2
]}

机构：

[1] China Agr Univ, Coll Food Sci & Nutr Engn, Beijing 100083, Peoples R China

[2] Minist Agr, Key Lab Safety Assessment Genetically Modified Or, Beijing 100083, Peoples R China

[3] Guangzhou Univ, Guangdong Prov Key Lab Radionuclides Pollut Contr, Guangzhou 510006, Peoples R China

来源：

DYES AND PIGMENTS | 2020年 / 180卷 / 180期

基金：

中国国家自然科学基金;

关键词：

Protamine; Perylene diimide; Rapid detection; Aggregation; Biosensor; FLUORESCENT SENSOR; BISIMIDE DYES; ULTRASENSITIVE DETECTION; SENSITIVE DETECTION; TRYPSIN-INHIBITOR; PHOSPHORESCENCE; NANOPARTICLES; SEPARATION; HEPARIN; FACILE;

D O I：

10.1016/j.dyepig.2020.108456

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

In this report, a water soluble perylene diimide derivative (PDI-Glu) was designed and prepared for rapid and visual detection of protamine. The sensing performance and mechanism of this probe toward protamine was investigated systematically by absorption and emission spectroscopic techniques. The fluorescence quenching caused by the aggregation of PDI-Glu in the presence of protamine could be outputted by spectrometer and observed by naked eyes. This method showed an excellent selectivity towards protamine in comparison of other analytes. It also featured good water solubility, large operable range, fast and visualized detection. The detection limit of protamine was calculated to be 0.09 mu g mL(-1). Finally, this probe can be also applied in serum samples and monitoring trypsin activity.

引用

页数：5

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