Autologous Hematopoietic Recovery after Unrelated Umbilical Cord Blood Transplantation with Myeloablative Conditioning for Acute Myelogenous Leukemia

被引：2

作者：

Gomyo, Ayumi ^{[1
]}

Nakasone, Hideki ^{[1
]}

Wada, Hidenori ^{[1
]}

Kawamura, Shunto ^{[1
]}

Yoshino, Nozomu ^{[1
]}

Takeshita, Junko ^{[1
]}

Yoshimura, Kazuki ^{[1
]}

Misaki, Yukiko ^{[1
]}

Tanihara, Aki ^{[1
]}

Akahoshi, Yu ^{[1
]}

Kusuda, Machiko ^{[1
]}

Tamaki, Masaharu ^{[1
]}

Kawamura, Koji ^{[1
]}

Kimura, Shun-ichi ^{[1
]}

Kako, Shinichi ^{[1
]}

Kanda, Yoshinobu ^{[1
]}

机构：

[1] Jichi Med Univ, Saitama Med Ctr, Div Hematol, Shimotsuke, Tochigi, Japan

来源：

INTERNAL MEDICINE | 2020年 / 59卷 / 19期

关键词：

autologous hematopoietic recovery; myeloablative conditioning; BONE-MARROW-TRANSPLANTATION; GRAFT FAILURE; HLA DISPARITY; ENGRAFTMENT; REMISSION; BUSULFAN; IMPACT; RECONSTITUTION; RECIPIENTS; REGIMEN;

D O I：

10.2169/internalmedicine.4829-20

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Autologous hematopoietic recovery after allogeneic hematopoietic cell transplantation (allo-HCT) is rare in patients who receive myeloablative conditioning (MAC). Autologous hematopoietic recovery suggests graft rejection, leading to concerns about subsequent disease relapse. We herein report a rare case of a patient with acute leukemia who experienced autologous hematopoietic recovery after cord blood transplantation (CBT) with total body irradiation-based MAC. Chromosomal abnormalities were repeatedly detected without any disease relapse for eight months. The accumulation of similar cases is required to accurately assess the incidence and clinical outcomes of autologous hematopoietic recovery after CBT with MAC.

引用

页码：2409 / 2414

页数：6

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