Adaptive designs in clinical trials in critically ill patients: principles, advantages and pitfalls

被引：15
作者：
van Werkhoven, C. H. [1 ]
Harbarth, S. [2 ,3 ,4 ,5 ]
Bonten, M. J. M. [1 ,6 ]
机构：
[1] Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, Heidelberglaan 100, NL-3584 CX Utrecht, Netherlands
[2] Geneva Univ Hosp, Infect Control Program, Geneva, Switzerland
[3] Geneva Univ Hosp, WHO Collaborating Ctr, Geneva, Switzerland
[4] Fac Med, Geneva, Switzerland
[5] Geneva Univ Hosp, Div Infect Dis, Geneva, Switzerland
[6] Univ Med Ctr Utrecht, Dept Med Microbiol, Utrecht, Netherlands
来源：
INTENSIVE CARE MEDICINE | 2019年 / 45卷 / 05期
关键词：
SEPTIC SHOCK; THERAPY;
D O I：
10.1007/s00134-018-5426-z
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
[No abstract available]
引用
收藏
页码：678 / 682
页数：5
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