Eosinophilic Lung Diseases

被引：47
作者：
Cottin, Vincent [1 ,2 ]
Cordier, Jean-Francois [1 ,2 ]
机构：
[1] Hop Louis Pradel, Hosp Civils Lyon, Serv Pneumol, Ctr Reference Natl Malad Pulm Rares, F-69677 Lyon, France
[2] Univ Lyon 1, INRA, INRA Vetagrosup EPHE IFR 128 UMR754, F-69365 Lyon, France
来源：
IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA | 2012年 / 32卷 / 04期
关键词：
Eosinophil; Eosinophilic pneumonia; Interstitial lung disease; Churg-Strauss syndrome; Aspergillus; CHURG-STRAUSS-SYNDROME; ALLERGIC BRONCHOPULMONARY ASPERGILLOSIS; TERM-FOLLOW-UP; ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES; RECEPTOR ANTAGONIST THERAPY; PNEUMONIA SHOWING TOLERANCE; ACUTE RESPIRATORY-FAILURE; ANTI-IGE ANTIBODY; THIN-SECTION CT; CYSTIC-FIBROSIS;
D O I：
10.1016/j.iac.2012.08.007
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
Eosinophilic lung diseases comprise eosinophilic pneumonia, which may present with chronic or acute onset, or as Loffler syndrome. The diagnosis of eosinophilic pneumonia relies on clinical imaging and the demonstration of alveolar eosinophilia. Lung biopsy is generally not necessary. Peripheral blood eosinophilia is common but may be absent at presentation in idiopathic acute eosinophilic pneumonia, which may be misdiagnosed as severe infectious pneumonia. Extra-thoracic manifestations should raise the suspicion of Churg-Strauss syndrome. All possible causes of eosinophilia (especially fungus infection or drug or toxic exposure) must be thoroughly investigated before the diagnosis of idiopathic disease is made.
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页码：557 / +
页数：31
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