Convenient method for the 3-functionalization of isoindazoles

被引：20

作者：

Bunnell, A ^{[1
]}

O'Yang, C ^{[1
]}

Petrica, A ^{[1
]}

Soth, MJ ^{[1
]}

机构：

[1] Roche Palo Alto LLC, Dept Med Chem, Palo Alto, CA 94304 USA

来源：

SYNTHETIC COMMUNICATIONS | 2006年 / 36卷 / 03期

关键词：

deprotonation; functionalization; 2H-indazoles; isoindazoles;

D O I：

10.1080/00397910500376570

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The C-3 position of isoindazoles is readily functionalized by metalation with lithium diisopropylamide followed by reaction with a variety of electrophiles.

引用

页码：285 / 293

页数：9

共 18 条

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