Nucleotide Composition of the Genomic and Protein-Coding Sequences in the two DNA Strands

被引：0
|
作者：
Nakashima, H. [1 ]
机构：
[1] Kanazawa Univ, Div Hlth Sci, Grad Course Med Sci & Technol, Dept Clin Lab Sci, Kanazawa, Ishikawa 9200942, Japan
来源：
4TH KUALA LUMPUR INTERNATIONAL CONFERENCE ON BIOMEDICAL ENGINEERING 2008, VOLS 1 AND 2 | 2008年 / 21卷 / 1-2期
关键词：
nucleotide composition; compositional asymmetry; leading and lagging strands; cumulative GC skew;
D O I：
暂无
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
The nucleotide composition of protein-coding genes in the two DNA strands of Escherichia coli, Bacillus subtilis, Methanococcus jannaschii and mitochondrial genes of human and fruit fly was studied. E. coli, B. subtilis and M. jannaschii indicated compositional asymmetry in their genomic sequences. The protein-coding genes of E. coli and B. subtilis showed the influence of compositional asymmetry in their compositions, however, no influence was observed in M. jannaschii. Mitochondrial protein-coding genes showed significant difference in composition in the two DNA strands. The deviation of nucleotide composition in the two DNA strands is discussed.
引用
收藏
页码：867 / 870
页数：4
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