ANTI-VIRUS RESPONSE AND INTERFERON, CYTOKINE SYSTEMS IN PATIENTS WITH CHRONIC HEPATITIS C

被引：0

作者：

Makashova, V. V. ^{[1
]}

Floryanu, A., I ^{[1
]}

机构：

[1] Cent Sci Res Inst Epidemiol, Moscow, Russia

来源：

TERAPEVTICHESKII ARKHIV | 2008年 / 80卷 / 11期

关键词：

chronic hepatitis C; interferons; cytokines; anti-virus response;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Aim. Determination of interferon and cytokine indices in patients with chronic virus hepatitis C. Material and methods. The significance of interferon and cytokine indices in patients with chronic viral hepatitis C (VHC) as criteria of efficacy of antiviral therapy was studied in 87 patients with chronic VHC. Results. High efficacy of interferon and ribamidil preparations against HCV is shown. Correlations between interferon and cytokine indices confirmed development of immune response by a Th1-type in responders. Conclusion. Interferon and cytokine profiles before the treatment and in its course are proposed as criteria of antivirus treatment efficacy in chronic VHC patients.

引用

页码：7 / 10

页数：4

共 14 条

[1]

Abayli Bahri, 2003, Turk J Gastroenterol, V14, P7

[2] Immunological predictors of different responses to combination therapy with interferon α and ribavirin in patients with chronic hepatitis C [J].

Amaraa, R ;

Mareckova, H ;

Urbanek, P ;

Fucikova, T .

JOURNAL OF GASTROENTEROLOGY, 2003, 38 (03) :254-259

[3]

BADYA SA, 2000, PROGNOST ZNACH KLIN

[4]

BLYUM KE, 2005, ROS ZH GASTROENTEROL, V1, P20

[5] Production of interleukins 10 and 12 by peripheral blood mononuclear cells (PBMC) in chronic hepatitis C virus (HCV) infection [J].

Kakumu, S ;

Okumura, A ;

Ishikawa, T ;

Iwata, K ;

Yano, M ;

Yoshioka, K .

CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 1997, 108 (01) :138-143

[6]

KURAMSHIN DK, 2001, ZH MIKROBIOL, V1, P57

[7] Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C [J].

McHutchison, JG ;

Gordon, SC ;

Schiff, ER ;

Shiffman, ML ;

Lee, WM ;

Rustgi, VK ;

Goodman, ZD ;

Ling, MH ;

Cort, S ;

Albrecht, JK .

NEW ENGLAND JOURNAL OF MEDICINE, 1998, 339 (21) :1485-1492

[8]

Neuman Manuela G, 2002, Rom J Gastroenterol, V11, P97

[9]

PAVLOVA LY, 2002, KLIN PROGNOZ ZNAVH P

[10]

SHULPEKOVA YB, 2002, MED IMMUNOL, V4, P268

← 1 2 →