Multiple Evanescent White Dot Syndrome Developing Three Days following Administration of mRNA-1273 Booster Vaccine: Case Report

被引:8
作者
Alhabshan, Rashed [1 ]
Scales, David [2 ]
机构
[1] South Texas Retina Consultants, Corpus Christi, TX 78413 USA
[2] Retina & Uveitis Consultants Texas, San Antonio, TX USA
关键词
COVID-19; Multiple evanescent white dot syndrome; mRNA vaccine;
D O I
10.1159/000525687
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Little is known about the potential ocular adverse events following mRNA-1273 vaccine. We aimed to report a case of multiple evanescent white dot syndrome (MEWDS) developing 3 days following the administration of mRNA-1273 vaccine booster. A 71-year-old white myopic female presented with complaints of seeing "pulsating light" and scotoma with her left eye that started about 3 days following mRNA-1273 vaccine booster administration. The patient was found to have multiple scattered white-yellow outer retinal lesions on dilated fundus exam of the left eye. Visual symptoms and exam findings continued to improve without any intervention confirming a short-lived and self-limiting disease course. Clinical presentation was consistent with a clinical diagnosis of MEWDS. Ophthalmologists need to take detailed vaccination history in patients presenting with MEWDS.
引用
收藏
页码:570 / 577
页数:8
相关论文
共 18 条
[1]   Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine [J].
Baden, Lindsey R. ;
El Sahly, Hana M. ;
Essink, Brandon ;
Kotloff, Karen ;
Frey, Sharon ;
Novak, Rick ;
Diemert, David ;
Spector, Stephen A. ;
Rouphael, Nadine ;
Creech, C. Buddy ;
McGettigan, John ;
Khetan, Shishir ;
Segall, Nathan ;
Solis, Joel ;
Brosz, Adam ;
Fierro, Carlos ;
Schwartz, Howard ;
Neuzil, Kathleen ;
Corey, Larry ;
Gilbert, Peter ;
Janes, Holly ;
Follmann, Dean ;
Marovich, Mary ;
Mascola, John ;
Polakowski, Laura ;
Ledgerwood, Julie ;
Graham, Barney S. ;
Bennett, Hamilton ;
Pajon, Rolando ;
Knightly, Conor ;
Leav, Brett ;
Deng, Weiping ;
Zhou, Honghong ;
Han, Shu ;
Ivarsson, Melanie ;
Miller, Jacqueline ;
Zaks, Tal .
NEW ENGLAND JOURNAL OF MEDICINE, 2021, 384 (05) :403-416
[2]   Multiple evanescent white dot syndrome after hepatitis B vaccine [J].
Baglivo, E ;
Safran, AB ;
Borruat, FX .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 1996, 122 (03) :431-432
[3]   Uveitis and Other Ocular Complications Following COVID-19 Vaccination [J].
Bolletta, Elena ;
Iannetta, Danilo ;
Mastrofilippo, Valentina ;
De Simone, Luca ;
Gozzi, Fabrizio ;
Croci, Stefania ;
Bonacini, Martina ;
Belloni, Lucia ;
Zerbini, Alessandro ;
Adani, Chantal ;
Fontana, Luigi ;
Salvarani, Carlo ;
Cimino, Luca .
JOURNAL OF CLINICAL MEDICINE, 2021, 10 (24)
[4]  
dell'Omo Roberto, 2012, Int Ophthalmol Clin, V52, P221, DOI 10.1097/IIO.0b013e31826647ed
[5]   An mRNA Vaccine against SARS-CoV-2-Preliminary Report [J].
Jackson, L. A. ;
Anderson, E. J. ;
Rouphael, N. G. ;
Roberts, P. C. ;
Makhene, M. ;
Coler, R. N. ;
McCullough, M. P. ;
Chappell, J. D. ;
Denison, M. R. ;
Stevens, L. J. ;
Pruijssers, A. J. ;
McDermott, A. ;
Flach, B. ;
Doria-Rose, N. A. ;
Corbett, K. S. ;
Morabito, K. M. ;
O'Dell, S. ;
Schmidt, S. D. ;
Swanson, P. A. ;
Padilla, M. ;
Mascola, J. R. ;
Neuzil, K. M. ;
Bennett, H. ;
Sun, W. ;
Peters, E. ;
Makowski, M. ;
Albert, J. ;
Cross, K. ;
Buchanan, W. ;
Pikaart-Tautges, R. ;
Ledgerwood, J. E. ;
Graham, B. S. ;
Beigel, J. H. .
NEW ENGLAND JOURNAL OF MEDICINE, 2020, 383 (20) :1920-1931
[6]   COVID-19, COVID-19 Vaccinations, and Subsequent Abnormalities in the Retina Causation or Coincidence? [J].
Jampol, Lee M. ;
Tauscher, Robert ;
Schwarz, Hans Peter .
JAMA OPHTHALMOLOGY, 2021, 139 (10) :1135-1136
[7]   The Advisory Committee on Immunization Practices' Interim Recommendations for Additional Primary and Booster Doses of COVID-19 Vaccines - United States, 2021 [J].
Mbaeyi, Sarah ;
Oliver, Sara E. ;
Collins, Jennifer P. ;
Godfrey, Monica ;
Goswami, Neela D. ;
Hadler, Stephen C. ;
Jones, Jefferson ;
Moline, Heidi ;
Moulia, Danielle ;
Reddy, Sujan ;
Schmit, Kristine ;
Wallace, Megan ;
Chamberland, Mary ;
Campos-Outcalt, Doug ;
Morgan, Rebecca L. ;
Bell, Beth P. ;
Brooks, Oliver ;
Kotton, Camille ;
Talbot, H. Keipp ;
Lee, Grace ;
Daley, Matthew F. ;
Dooling, Kathleen .
MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT, 2021, 70 (44) :1545-1552
[8]  
Ng Caleb C, 2020, Am J Ophthalmol Case Rep, V19, P100845, DOI 10.1016/j.ajoc.2020.100845
[9]   Multiple Evanescent White Dot Syndrome after Human Papillomavirus Vaccination [J].
Ogino, Ken ;
Kishi, Shoji ;
Yoshimura, Nagahisa .
CASE REPORTS IN OPHTHALMOLOGY, 2014, 5 (01) :38-43
[10]   Multiple evanescent white dot syndrome (MEWDS): update on practical appraisal, diagnosis and clinicopathology; a review and an alternative comprehensive perspective [J].
Papasavvas, Ioannis ;
Mantovani, Alessandro ;
Tugal-Tutkun, Ilknur ;
Herbort, Carl P., Jr. .
JOURNAL OF OPHTHALMIC INFLAMMATION AND INFECTION, 2021, 11 (01)