t(1;19)(q23;p13) in a case of acute monocytic leukemia

被引：3

作者：

Weh, HJ

Jonveaux, P

Seeger, D

Felgner, J

Hossfeld, DK

机构：

[1] INST GENET MOLEC,INSERM U301,PARIS,FRANCE

[2] CHRISTIAN ALBRECHTS UNIV KIEL,INST HEMATOPATHOL,KIEL,GERMANY

来源：

CANCER GENETICS AND CYTOGENETICS | 1996年 / 87卷 / 01期

关键词：

D O I：

10.1016/0165-4608(95)00238-3

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Translocation (1;19)(q23;p13) is considered a specific chromosome aberration in acute lymphoblastic leukemia (ALL). We report a case of M5 acute nonlymphocytic leukemia (ANLL) with t(1;19). In all mitoses studied from peripheral blood (PB) cells, the pathological karyotype 51,XX, t(1;19)(q23;p13), + 8, + der(19)t(1;19)(q23;p13), + 3mar was detected. No rearrangement of the E2A gene was detected. We believe this case shows that cytogenetically indistinguishable aberrations may be accompanied by quite different molecular events.

引用

页码：52 / 54

页数：3

共 16 条

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