Metastases to the pituitary gland

被引:24
作者
Heshmati, HM
Scheithauer, BW
Young, WF
机构
[1] Mayo Clin, Div Endocrinol Metab Nutr & Internal Med, Rochester, MN 55905 USA
[2] Mayo Clin, Surg Pathol Sect, Rochester, MN 55905 USA
[3] Sanofi Synthelabo Res, Clin Dev, Malvern, PA USA
关键词
D O I
10.1097/00019616-200201000-00010
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Pituitary metastasis is a rare cause of an intrasellar mass. The authors report a series of 52 patients with intrasellar metastases diagnosed between 1950 and 1996. The patient group included 29 women and 23 men with a mean age of 60 years. Breast and lung carcinomas were the most frequent primary tumors (37% and 23%, respectively). The primary tumor was unknown in 12% of patients. In the patients with a known primary tumor, it was diagnosed after the pituitary metastasis was discovered in 20%. The mode of discovery of pituitary metastases was symptom-based (visual impairment, diabetes insipidus, hypopituitarism) in 75% of patients. Of the patients in whom prolactin was measured, 63% had hyperprolactinemia. Computed tomography and magnetic resonance imaging of the brain, available for 52% and 19% of patients, respectively, showed a pituitary mass in each case. Pituitary surgery and radiotherapy were performed in 42% and 63% of patients, respectively. Mean survival was 17 months (range, 0-240 months). Overall mortality at 1 year was 67%.
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收藏
页码:45 / 49
页数:7
相关论文
共 35 条
  • [1] Renal carcinoma presenting with adrenocortical insufficiency due to a pituitary metastasis
    Beckett, DJ
    Gama, R
    Wright, J
    Ferns, GAA
    [J]. ANNALS OF CLINICAL BIOCHEMISTRY, 1998, 35 : 542 - 544
  • [2] INTRASELLAR METASTASIS MIMICKING A PITUITARY-ADENOMA
    BUONAGUIDI, R
    FERDEGHINI, M
    FAGGIONATO, F
    TUSINI, G
    [J]. SURGICAL NEUROLOGY, 1983, 20 (05): : 373 - 378
  • [3] Central diabetes insipidus and Cushing's syndrome due to ectopic ACTH production by disseminated small cell lung cancer: A case report
    Cabezas, MC
    Vrinten, DH
    Burgers, JA
    Croughs, RJM
    [J]. NETHERLANDS JOURNAL OF MEDICINE, 1998, 53 (01) : 32 - 36
  • [4] CHBICHEB M, 1991, PRESSE MED, V20, P1234
  • [5] CLAVIER H, 1987, REV MAL RESPIR, V4, P185
  • [6] CHIASMAL SYNDROME DUE TO METASTASIS
    COHEN, MM
    LESSELL, S
    [J]. ARCHIVES OF NEUROLOGY, 1979, 36 (09) : 565 - 567
  • [7] Coppola A, 1989, Minerva Med, V80, P1119
  • [8] CRYAR A K, 1987, Henry Ford Hospital Medical Journal, V35, P185
  • [9] Decanter C, 1996, ANN ENDOCRINOL-PARIS, V57, P411
  • [10] Pituitary metastasis from carcinoma of the urinary bladder mimicking pituitary apoplexy - Case report
    Furuta, S
    Hatakeyama, T
    Zenke, K
    Fukumoto, S
    [J]. NEUROLOGIA MEDICO-CHIRURGICA, 1999, 39 (02): : 165 - 168