Hydrochlorotiazide-induced acute non-cardiogenic pulmonary edema

被引:0
作者
Gamboa, PM
Achotegui, V
Irigoyen, J
Pérez-Asenjo, J
Merino, J
Sanz, ML
机构
[1] Hosp Basurto, Serv Alergol, Bilbao 48013, Spain
[2] Hosp Cruces, Serv Neumol, Bilbao, Spain
[3] Hosp Cruces, Serv Cardiol, Bilbao, Spain
[4] Univ Navarra, Univ Clin, Dept Immunol, E-31080 Pamplona, Spain
[5] Univ Navarra, Univ Clin, Dept Allergol & Clin Immunol, E-31080 Pamplona, Spain
关键词
hydrochlorothiazide; lung edema; side effects;
D O I
暂无
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
We report the case of a 64 year-old male with non cardiogenic pulmonary edema episodes after oral administration of 12.5 mg of hydrochlorotiazide. In vitro immunologic study with basophil activation test and late cellular activation study (CD69 and production of interferon gamma) with chlorotiazide were performed, and no activation was observed. As a consequence, like in previous cases published, the pathogenic mechanism remains unknown, and it probably is an idiosyncratic reaction.
引用
收藏
页码:299 / 301
页数:3
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