ALZHEIMER'S DISEASE A breach in the blood-brain barrier

被引：20

作者：

Carmeliet, Peter ^{[1
]}

De Strooper, Bart ^{[2
,3
]}

机构：

[1] Katholieke Univ Leuven VIB, Vesalius Res Ctr, B-3000 Louvain, Belgium

[2] Katholieke Univ Leuven VIB, Ctr Biol Dis, B-3000 Louvain, Belgium

[3] Katholieke Univ Leuven, Ctr Human Genet, B-3000 Louvain, Belgium

来源：

NATURE | 2012年 / 485卷 / 7399期

关键词：

THERAPEUTICS; DISORDERS; APOE;

D O I：

10.1038/485451a

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Alterations in brain blood vessels in mice precede the neural dysfunction associated with Alzheimer's disease. The finding highlights potential targets for drug development. See Letter p.512

引用

页码：451 / 452

页数：2

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