Ventilatory and Pharmacotherapeutic Strategies for Management of Adult Patients on Extracorporeal Life Support

被引：10

作者：

Dzierba, Amy L. ^{[1
]}

Abrams, Darryl ^{[2
]}

Muir, Justin ^{[1
]}

Brodie, Daniel ^{[2
]}

机构：

[1] NewYork Presbyterian Hosp, Dept Pharm, New York, NY USA

[2] Columbia Univ, Div Pulm Allergy & Crit Care, Coll Phys & Surg, NewYork Presbyterian Hosp, New York, NY USA

来源：

PHARMACOTHERAPY | 2019年 / 39卷 / 03期

关键词：

extracorporeal life support; ECLS; anticoagulation; pharmacokinetics; RESPIRATORY-DISTRESS-SYNDROME; PARTIAL THROMBOPLASTIN TIME; MEMBRANE-OXYGENATION; MECHANICAL VENTILATION; LUNG TRANSPLANTATION; 6; ML/KG; FAILURE; SEDATION; HEPARIN; ANTICOAGULATION;

D O I：

10.1002/phar.2230

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Extracorporeal life support (ECLS) can provide mechanical support for patients with severe life-threatening cardiac or respiratory failure. ECLS is a complex therapy that has increased in use over several decades owing to advances in technology. In concert with this growth, there is an increased need to understand the complexity of this technology to augment the effectiveness of ECLS and minimize complications such as ventilator-induced lung injury, bleeding, thrombosis, infections, and inadequate drug dosing. The purpose of this review was to discuss management strategies in adult patients receiving ECLS and provide recommendations on ventilator management, provision of adequate analgesia and sedation, treatment and prevention of infections, and anticoagulation.

引用

页码：355 / 368

页数：14

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