Functional (Psychogenic) Symptoms in Parkinson's Disease

被引:45
作者
Parees, Isabel [1 ]
Saifee, Tabish A. [1 ]
Kojovic, Maja [1 ,2 ]
Kassavetis, Panagiotis [1 ]
Rubio-Agusti, Ignacio [1 ,3 ]
Sadnicka, Anna [1 ]
Bhatia, Kailash P. [1 ]
Edwards, Mark J. [1 ]
机构
[1] UCL Inst Neurol, Sobell Dept Motor Neurosci & Movement Disorders, London WC1N 3BG, England
[2] Univ Ljubljana, Dept Neurol, Ljubljana, Slovenia
[3] Hosp Univ La Fe, Dept Neurol, Movement Disorders Unit, Valencia, Spain
关键词
Parkinson's disease; functional overlay; attention; goal-directed motor control; CONVERSION PARALYSIS; SOMATOFORM DISORDERS; LEWY BODIES; FREE-ENERGY; ATTENTION; DEMENTIA; TREMOR;
D O I
10.1002/mds.25544
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
It has been reported that patients who have Parkinson's disease have a high prevalence of somatisation (functional neurological symptoms) compared with patients who have other neurodegenerative conditions. Numerous explanations have been advanced for this phenomenon. Here, with illustrative cases, we discuss this topic, including its clinical importance, and suggest a link between the pathophysiology of Parkinson's disease and the proposed propensity to develop functional symptoms. (c) 2013 International Parkinson and Movement Disorder Society
引用
收藏
页码:1622 / 1627
页数:6
相关论文
共 24 条
[1]   Motor inhibition in hysterical conversion paralysis [J].
Cojan, Yann ;
Waber, Lakshmi ;
Carruzzo, Alain ;
Vuilleumier, Patrik .
NEUROIMAGE, 2009, 47 (03) :1026-1037
[2]   Neuropsychological correlates of alexithyrnia in Parkinson's disease [J].
Costa, Alberto ;
Peppe, Antonella ;
Carlesimo, Giovanni Augusto ;
Salamone, Giovanna ;
Caltagirone, Carlo .
JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY, 2007, 13 (06) :980-992
[3]  
Edwards MJ, 2012, BRAIN 11, V135, P34953
[4]  
Fahn S, 1988, Adv Neurol, V50, P431
[5]   Attention, uncertainty, and free-energy [J].
Feldman, Harriet ;
Friston, Karl J. .
FRONTIERS IN HUMAN NEUROSCIENCE, 2010, 4
[6]   Limited conscious monitoring of motor performance in normal subjects [J].
Fourneret, P ;
Jeannerod, M .
NEUROPSYCHOLOGIA, 1998, 36 (11) :1133-1140
[7]   Action and behavior: a free-energy formulation [J].
Friston, Karl J. ;
Daunizeau, Jean ;
Kilner, James ;
Kiebel, Stefan J. .
BIOLOGICAL CYBERNETICS, 2010, 102 (03) :227-260
[8]   Placebo response in Parkinson's disease: Comparisons among 11 trials covering medical and surgical interventions [J].
Goetz, Christopher G. ;
Wuu, Joanne ;
McDermott, Michael P. ;
Adler, Charles H. ;
Fahn, Stanley ;
Freed, Curt R. ;
Hauser, Robert A. ;
Olanow, Warren C. ;
Shoulson, Ira ;
Tandon, P. K. ;
Leurgans, Sue .
MOVEMENT DISORDERS, 2008, 23 (05) :690-699
[9]   Psychogenic parkinsonism [J].
Hallett, Mark .
JOURNAL OF THE NEUROLOGICAL SCIENCES, 2011, 310 (1-2) :163-165
[10]   ACCURACY OF CLINICAL-DIAGNOSIS OF IDIOPATHIC PARKINSONS-DISEASE - A CLINICOPATHOLOGICAL STUDY OF 100 CASES [J].
HUGHES, AJ ;
DANIEL, SE ;
KILFORD, L ;
LEES, AJ .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1992, 55 (03) :181-184