Nanoscale powders and formulations with biocidal activity toward spores and vegetative cells of Bacillus species, viruses, and toxins

被引:104
作者
Koper, OB
Klabunde, JS
Marchin, GL
Klabunde, KJ
Stoimenov, P
Bohra, L
机构
[1] Kansas State Univ, Div Biol, Manhattan, KS 66506 USA
[2] Nanoscale Mat Inc, Nantek Inc, Manhattan, KS 66502 USA
[3] Kansas State Univ, Dept Chem, Manhattan, KS 66506 USA
[4] Food Labs, Manhattan, KS 66502 USA
关键词
D O I
10.1007/s00284-001-0073-x
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Certain formulations of nanoscale powders possess antimicrobial properties. These formulations are made of simple, nontoxic metal oxides such as magnesium oxide (MgO) and calcium oxide (CaO, lime) in nanocrystalline form, carrying active forms of halogens, for example, MgO . Cl, and MgO . Br2. When these ultrafine powders contact vegetative cells of Escherichia coli, Bacillus cereus, or Bacillus globigii, over 90% are killed within a few minutes. Likewise, spore forms of the Bacillus species are decontaminated within several hours. Dry contact with aflatoxins and contact with MS2 bacteriophage (surrogate of human enterovirus) in water also causes decontamination in minutes.
引用
收藏
页码:49 / 55
页数:7
相关论文
共 9 条
[1]   A novel surfactant nanoemulsion with broad-spectrum sporicidal activity against Bacillus species [J].
Hamouda, T ;
Hayes, MM ;
Cao, ZY ;
Tonda, R ;
Johnson, K ;
Wright, DC ;
Brisker, J ;
Baker, JR .
JOURNAL OF INFECTIOUS DISEASES, 1999, 180 (06) :1939-1949
[2]   Nanocrystalline metal oxides as new adsorbents for air purification [J].
Khaleel, A ;
Kapoor, PN ;
Klabunde, KJ .
NANOSTRUCTURED MATERIALS, 1999, 11 (04) :459-468
[3]  
KLABUNDE KJ, 1999, Patent No. 5990373
[4]  
Koper O, 2000, US, Patent No. 6057488
[5]   Alkaline-earth oxide nanoparticles obtained by aerogel methods. Characterization and rational for unexpectedly high surface chemical reactivities [J].
Koper, OB ;
Lagadic, I ;
Volodin, A ;
Klabunde, KJ .
CHEMISTRY OF MATERIALS, 1997, 9 (11) :2468-2480
[6]   Nanocrystals as destructive adsorbants for mimcs of chemical warfare agents [J].
Lucas, EM ;
Klabunde, KJ .
NANOSTRUCTURED MATERIALS, 1999, 12 (1-4) :179-182
[7]   Consolidation of metal oxide nanocrystals. Reactive pellets with controllable pore structure that represent a new family of porous, inorganic materials [J].
Richards, R ;
Li, WF ;
Decker, S ;
Davidson, C ;
Koper, O ;
Zaikovski, V ;
Volodin, A ;
Rieker, T ;
Klabunde, KJ .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2000, 122 (20) :4921-4925
[8]   Nanocrystal metal oxide-chlorine adducts: Selective catalysts for chlorination of alkanes [J].
Sun, NJ ;
Klabunde, KJ .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (23) :5587-5588
[9]   NANOSCALE METAL-OXIDE PARTICLES CLUSTERS AS CHEMICAL REAGENTS - SYNTHESIS AND PROPERTIES OF ULTRAHIGH SURFACE-AREA MAGNESIUM-HYDROXIDE AND MAGNESIUM-OXIDE [J].
UTAMAPANYA, S ;
KLABUNDE, KJ ;
SCHLUP, JR .
CHEMISTRY OF MATERIALS, 1991, 3 (01) :175-181