Platelet ADP Receptors and their Antagonists

被引:5
|
作者
Benoit, Patricia [1 ]
Dogne, Jean-Michel [1 ]
机构
[1] Nat & Synthet Drugs Res Ctr Med Chem, B-4000 Liege, Belgium
关键词
Adenosine diphosphate; ADP receptors; P2; receptors; thienopyridine; antithrombotics; platelets;
D O I
10.2174/1389557033405412
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
ADP plays a crucial role in haemostasis and thrombosis and its receptors are potential target for antithrombotic drugs. The knowledge of the ADP-receptors has been amplified by recent discoveries. This review highlights the ADP-receptors models and their antagonists described in the recent literature, mainly the thienopyridine derivatives.
引用
收藏
页码:145 / 148
页数:4
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