Multitarget-directed ligands for neurodegenerative diseases: real opportunity or blurry mirage?

被引：18

作者：

Benchekroun, Mohamed ^{[1
]}

Maramai, Samuele ^{[2
]}

机构：

[1] Univ Paris Saclay, Inst Chim Subst Nat, CNRS, UPR 2301, Ave Terrasse, F-91198 Gif Sur Yvette, France

[2] Univ Sussex, Sussex Drug Discovery Ctr, Sch Life Sci, Brighton BN1 9QJ, E Sussex, England

来源：

FUTURE MEDICINAL CHEMISTRY | 2019年 / 11卷 / 04期

关键词：

beta-amyloid; Alzheimer's; drug discovery; inhibitor; metal dishomeostasis; mitochondria; multitarget-directed ligands; neurodegenerative diseases; neuronal signaling; oxidative stress; ALZHEIMERS; INHIBITORS; TRIAL;

D O I：

10.4155/fmc-2018-0249

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：261 / 263

页数：3

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