Xenon anesthesia and beyond: pros and cons

被引：14

作者：

Jin, Zhaosheng ^{[1
]}

Piazza, Ornella ^{[2
]}

Ma, Daqing ^{[1
]}

Scarpati, Giuliana ^{[2
]}

De Robertis, Edoardo ^{[3
]}

机构：

[1] Imperial Coll London, Anesthet Pain Med & Intens Care, Dept Surg & Canc, Chelsea & Westminster Hosp, London, England

[2] Univ Salerno, Dept Med & Surg, Salerno, Italy

[3] Univ Naples Federico II, Dept Neurosci Reprod & Odontostomatol Sci, Via S Pansini 5, I-80131 Naples, Italy

来源：

MINERVA ANESTESIOLOGICA | 2019年 / 85卷 / 01期

关键词：

Xenon; General anesthesia; Postoperative nausea and vomiting; Delirium; MINIMUM ALVEOLAR CONCENTRATION; ISCHEMIA-REPERFUSION INJURY; D-ASPARTATE RECEPTOR; NITROUS-OXIDE; POSTOPERATIVE DELIRIUM; MALIGNANT HYPERTHERMIA; INTRANASAL APPLICATION; GENERAL-ANESTHESIA; TREATMENT PROTECTS; CONCENTRATION MAC;

D O I：

10.23736/S0375-9393.18.12909-9

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Xenon is a colorless and odorless noble gas, licensed for human use as an anesthetic gas as well as a radiological marker. The MAC of this gas is about 63% but xenon anesthesia is associated with fast recovery of cognitive function and cardiovascular stability. Nevertheless, postoperative nausea and vomiting (PONV) incidence for xenon anesthesia is very high. It has been reported that Xenon has cytoprotective effects that may have therapeutic values in both CNS protection, and in organ graft preservation. Currently, there are few studies about the effect of xenon on ischemia reperfusion injury of transplantable organs and insufficient clinical data upon its effect on intracranial and cerebral perfusion pressure. We shortly review the pros and cons of xenon as an anesthetic agent.

引用

页码：83 / 89

页数：7

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