Navigating the Folding Energy Landscape of Green Fluorescent Protein

被引：24
|
作者：
Bertz, Morten [1 ]
Kunfermann, Andrea [3 ]
Rief, Matthias [1 ,2 ]
机构：
[1] Tech Univ Munich, Phys Dept E22, D-85748 Garching, Germany
[2] Munich Ctr Integrated Prot Sci CiPSM, Munich, Germany
[3] Tech Univ Munich, Lehrstuhl Biophys Chem, Dept Chem, D-85748 Garching, Germany
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 43期
关键词：
protein engineering; protein folding; protein structures; scanning probe microscopy; single-molecule studies;
D O I：
10.1002/anie.200802987
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The directed application of force to different points on the surface of the green fluorescent protein (GFP) makes it possible to shift between two different pathways with distinct unfolding intermediates. One pathway resembles a "folding-like" pathway, whereas the other may play a role during processes such as import through a pore. The picture shows the energy landscape of GFP with intermediates and pathways. (Figure Presented) © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码：8192 / 8195
页数：4
相关论文
共 50 条
  • [1] Navigating the protein folding energy landscape
    Socci, ND
    Onuchic, JN
    BIOPHYSICAL JOURNAL, 1996, 70 (02) : WAML7 - WAML7
  • [2] Green fluorescent protein as a reporter of prion protein folding
    Snezana Vasiljevic
    Junyuan Ren
    YongXiu Yao
    Kevin Dalton
    Catherine S Adamson
    Ian M Jones
    Virology Journal, 3
  • [3] Green fluorescent protein as a reporter of prion protein folding
    Vasiljevic, Snezana
    Ren, Junyuan
    Yao, YongXiu
    Dalton, Kevin
    Adamson, Catherine S.
    Jones, Ian M.
    VIROLOGY JOURNAL, 2006, 3 (1)
  • [4] Navigating the RNA folding landscape
    Gonzalez, Ruben L., Jr.
    NATURE CHEMICAL BIOLOGY, 2008, 4 (08) : 451 - 452
  • [5] Navigating the RNA folding landscape
    Ruben L Gonzalez
    Nature Chemical Biology, 2008, 4 : 451 - 452
  • [6] Energy landscape in protein folding and unfolding
    Mallamace, Francesco
    Corsaro, Carmelo
    Mallamace, Domenico
    Vasi, Sebastiano
    Vasi, Cirino
    Baglioni, Piero
    Buldyrev, Sergey V.
    Chen, Sow-Hsin
    Stanley, H. Eugene
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2016, 113 (12) : 3159 - 3163
  • [7] Energy Landscape of Knotted Protein Folding
    Sulkowska, Joanna I.
    Noel, Jeff K.
    Onuchic, Jose N.
    BIOPHYSICAL JOURNAL, 2013, 104 (02) : 370A - 370A
  • [8] Energy landscape of knotted protein folding
    Sulkowska, Joanna I.
    Noel, Jeffrey K.
    Onuchic, Jose N.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, 109 (44) : 17783 - 17788
  • [9] Folding and unfolding of a non-fluorescent mutant of green fluorescent protein
    Wielgus-Kutrowska, Beata
    Narczyk, Marta
    Buszko, Anna
    Bzowska, Agnieszka
    Clark, Patricia L.
    JOURNAL OF PHYSICS-CONDENSED MATTER, 2007, 19 (28)
  • [10] Chaperonin-mediated folding of green fluorescent protein
    Makino, Y
    Amada, K
    Taguchi, H
    Yoshida, M
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (19) : 12468 - 12474
12345