Genetic Issues in Patients with Breast Cancer

被引：3

作者：

Fossland, Victoria Sahadevan ^{[5
]}

Stroop, Jennifer B. ^{[1
]}

Schwartz, Robin C. ^{[2
]}

Kurtzman, Scott H. ^{[3
,4
,5
]}

机构：

[1] Univ Connecticut, Carole & Ray Neag Comprehens Canc Ctr, Div Human Genet, Dept Genet & Dev Biol,Sch Med, Farmington, CT USA

[2] Univ Connecticut, Carole & Ray Neag Comprehens Canc Ctr, Div Human Genet, Dept Genet & Dev Biol & Pediat,Sch Med, Farmington, CT USA

[3] Univ Connecticut, Sch Med, Dept Surg, Ctr Hlth, Farmington, CT 06032 USA

[4] Univ Connecticut, Sch Med, Carol & Ray Neag Comprehens Canc Ctr, Ctr Hlth, Farmington, CT 06032 USA

[5] Waterbury Hosp & Hlth Ctr, Dept Surg, Ctr Hlth, Waterbury, CT 06721 USA

来源：

SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA | 2009年 / 18卷 / 01期

关键词：

Breast cancer; Genetics; Psychosocial support; SURGICAL ADJUVANT BREAST; CONTRALATERAL PROPHYLACTIC MASTECTOMY; REDUCING SALPINGO-OOPHORECTOMY; BRCA2 MUTATION CARRIERS; QUALITY-OF-LIFE; HEREDITARY BREAST; OVARIAN-CANCER; GERMLINE MUTATIONS; CLINICAL CHARACTERISTICS; RISK-ASSESSMENT;

D O I：

10.1016/j.soc.2008.08.008

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Screening for genetic abnormalities is a relatively complex task requiring detailed training and knowledge. Analysis of a person's genetic makeup has implications not only for that individual but also for their progenitors, offspring, siblings, and spouses. There are potential insurance, employment, and other risks regarding disclosure of this information. With proper training, surgeons or nurses with advanced skills can be qualified to conduct this type of initial analysis. Geneticists may be the ideal professionals to counsel patients. In this article, we explore these and other issues. The goal is to provide the surgeon with the information needed to identify patients at risk for carrying identifiable mutations that might lead to the development of breast cancer.

引用

页码：53 / +

页数：20

共 84 条

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