Endogenous huntingtin modulates the cellular toxicity of mutant huntingtin.

被引：0
|
作者：
Leavitt, BR
Hackam, A
Gutekunst, CA
McCutcheon, K
Yassa, A
Singaraja, R
Kimel, G
Hersch, S
Vogl, W
Hayden, MR
机构：
[1] UBC, CMMT, Vancouver, BC, Canada
[2] Emory Univ, Sch Med, Atlanta, GA USA
[3] Univ British Columbia, Dept Anat, Vancouver, BC V6T 1W5, Canada
来源：
AMERICAN JOURNAL OF HUMAN GENETICS | 1999年 / 65卷 / 04期
关键词：
D O I：
暂无
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
2591
引用
收藏
页码：A457 / A457
页数：1
相关论文
共 50 条
  • [1] A Novel Translational Bioassay for Conformers of Mutant Huntingtin.
    Moscovitch-Lopatin, M.
    DiFiglia, M.
    Kegel-Gleason, K.
    Ritch, J. J.
    Rosenthal, S. J.
    Sapp, E.
    Wheelock, V.
    Duffy, A.
    Chopra, V.
    Rosas, H. D.
    Hersch, S. M.
    NEUROTHERAPEUTICS, 2016, 13 (01) : 254 - 254
  • [2] Wild-type huntingtin reduces the cellular toxicity of mutant huntingtin in vivo
    Leavitt, BR
    Guttman, JA
    Hodgson, JG
    Kimel, GH
    Singaraja, R
    Vogl, AW
    Hayden, MR
    AMERICAN JOURNAL OF HUMAN GENETICS, 2001, 68 (02) : 313 - 324
  • [3] Transcriptional regulation by huntingtin.
    Jones, L
    Duce, J
    Hartog, C
    Elliston, L
    Caswell, R
    Wilkinson, F
    Morris, GE
    Man, NT
    Neal, J
    Harper, PS
    AMERICAN JOURNAL OF HUMAN GENETICS, 2000, 67 (04) : 365 - 365
  • [4] Phosphorylation of Mutant Huntingtin at Serine 116 Modulates Neuronal Toxicity
    Watkin, Erin E.
    Arbez, Nicolas
    Waldron-Roby, Elaine
    O'Meally, Robert
    Ratovitski, Tamara
    Cole, Robert N.
    Ross, Christopher A.
    PLOS ONE, 2014, 9 (02):
  • [5] Wild type huntingtin reduces the cellular toxicity of mutant huntingtin in mammalian cell models of Huntington's disease
    Ho, LW
    Brown, R
    Maxwell, M
    Wyttenbach, A
    Rubinsztein, DC
    JOURNAL OF MEDICAL GENETICS, 2001, 38 (07) : 450 - 452
  • [6] Dynamic of inclusion formation and processing of huntingtin.
    Trottier, Y
    Lunkes, A
    Lindenberg, KS
    Devys, D
    Landwehrmeyer, GB
    Mandel, JL
    AMERICAN JOURNAL OF HUMAN GENETICS, 2001, 69 (04) : 616 - 616
  • [7] GLYCATION MODULATES HUNTINGTIN AGGREGATION AND TOXICITY
    Vicente Miranda, Hugo
    Gomes, M. A.
    Branco dos Santos, J.
    Giorgini, F.
    Outeiro, T. F.
    JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2014, 85 : A11 - A11
  • [8] Normal Aging Modulates the Neurotoxicity of Mutant Huntingtin
    Diguet, Elsa
    Petit, Fanny
    Escartin, Carole
    Cambon, Karine
    Bizat, Nicolas
    Dufour, Noelle
    Hantraye, Philippe
    Deglon, Nicole
    Brouillet, Emmanuel
    PLOS ONE, 2009, 4 (02):
  • [9] Rescue of aberrant huntingtin palmitoylation ameliorates mutant huntingtin-induced toxicity
    Lemarie, Fanny L.
    Caron, Nicholas S.
    Sanders, Shaun S.
    Schmidt, Mandi E.
    Nguyen, Yen T. N.
    Ko, Seunghyun
    Xu, Xiaohong
    Pouladi, Mahmoud A.
    Martin, Dale D. O.
    Hayden, Michael R.
    NEUROBIOLOGY OF DISEASE, 2021, 158
  • [10] Polyglutamine aggregation impairs nuclear export of huntingtin.
    Cornett, JC
    Li, SH
    Li, XJ
    AMERICAN JOURNAL OF HUMAN GENETICS, 2003, 73 (05) : 586 - 586
12345