Matriptase is highly upregulated in chronic lymphocytic leukemia and promotes cancer cell invasion

被引:19
作者
Gao, L. [1 ]
Liu, M. [1 ]
Dong, N. [1 ,2 ]
Jiang, Y. [1 ]
Lin, C-Y [3 ]
Huang, M. [4 ,5 ]
Wu, D. [2 ]
Wu, Q. [1 ,5 ,6 ]
机构
[1] Soochow Univ, Affiliated Hosp 1, Jiangsu Inst Hematol, Cyrus Tang Hematol Ctr, Suzhou, Peoples R China
[2] Soochow Univ, Thrombosis & Hemostasis Key Lab, Minist Hlth, Jiangsu Inst Hematol,Affiliated Hosp 1, Suzhou, Peoples R China
[3] Georgetown Univ, Sch Med, Lombardi Comprehens Canc Ctr, Washington, DC USA
[4] Chinese Acad Sci, Fujian Inst Res Struct Matter, State Key Lab Struct Chem, Fuzhou 350002, Peoples R China
[5] Danish Chinese Ctr Proteases & Canc, Cleveland, OH USA
[6] Cleveland Clin, Cleveland, OH 44106 USA
关键词
HEPATOCYTE GROWTH-FACTOR; SERINE-PROTEASE; ACTIVATION; HAI-1;
D O I
10.1038/leu.2012.289
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:1191 / 1194
页数:5
相关论文
共 15 条
[1]   Loss of membrane-bound serine protease inhibitor HAI-1 induces oral squamous cell carcinoma cells' invasiveness [J].
Baba, Takashi ;
Kawaguchi, Makiko ;
Fukushima, Tsuyoshi ;
Sato, Yuko ;
Orikawa, Hiroshi ;
Yorita, Kenji ;
Tanaka, Hiroyuki ;
Lin, Chen-Yong ;
Sakoda, Sumio ;
Kataoka, Hiroaki .
JOURNAL OF PATHOLOGY, 2012, 228 (02) :181-192
[2]   Type II Transmembrane Serine Proteases [J].
Bugge, Thomas H. ;
Antalis, Toni M. ;
Wu, Qingyu .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 284 (35) :23177-23181
[3]   MT-SP1 proteolysis and regulation of cell-microenvironment interactions [J].
Darragh, Molly R. ;
Bhatt, Ami S. ;
Craik, Charles S. .
FRONTIERS IN BIOSCIENCE-LANDMARK, 2008, 13 :528-539
[4]   New functions for the matrix metalloproteinases in cancer progression [J].
Egeblad, M ;
Werb, Z .
NATURE REVIEWS CANCER, 2002, 2 (03) :161-174
[5]   Initiation of plasminogen activation on the surface of monocytes expressing the type II transmembrane serine protease matriptase [J].
Kilpatrick, Lynette M. ;
Harris, Roger L. ;
Owen, Kate A. ;
Bass, Rosemary ;
Ghorayeb, Christine ;
Bar-Or, Amit ;
Ellis, Vincent .
BLOOD, 2006, 108 (08) :2616-2623
[6]   Epithin/PRSS14 proteolytically regulates angiopoietin receptor Tie2 during transendothelial migration [J].
Kim, Chungho ;
Lee, Hyo Seon ;
Lee, Deokjae ;
Lee, Sang Don ;
Cho, Eun-Gyung ;
Yang, Soo Jung ;
Kim, Sang Bum ;
Park, Dongeun ;
Kim, Moon Gyo .
BLOOD, 2011, 117 (04) :1415-1424
[7]   Tissue expression, protease specificity, and Kunitz domain functions of hepatocyte growth factor activator Inhibitor-1B (HAI-1B), a new splice variant of HAI-1 [J].
Kirchhofer, D ;
Peek, M ;
Li, W ;
Stamos, J ;
Eigenbrot, C ;
Kadkhodayan, S ;
Elliott, JM ;
Corpuz, RT ;
Lazarus, RA ;
Moran, P .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (38) :36341-36349
[8]   Activation of hepatocyte growth factor and urokinase/plasminogen activator by matriptase, an epithelial membrane serine protease [J].
Lee, SL ;
Dickson, RB ;
Lin, CY .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (47) :36720-36725
[9]   Zymogen activation, inhibition, and ectodomain shedding of matriptase [J].
Lin, Chen-Yong ;
Tseng, I-Chu ;
Chou, Feng-Pai ;
Su, Sheng-Fang ;
Chen, Ya-Wen ;
Johnson, Michael D. ;
Dickson, Robert B. .
FRONTIERS IN BIOSCIENCE-LANDMARK, 2008, 13 :621-635
[10]   Deregulated matriptase causes ras-independent multistage carcinogenesis and promotes ras-mediated malignant transformation [J].
List, K ;
Szabo, R ;
Molinolo, A ;
Sriuranpong, V ;
Redeye, V ;
Murdock, T ;
Burke, B ;
Nielsen, BS ;
Gutkind, JS ;
Bugge, TH .
GENES & DEVELOPMENT, 2005, 19 (16) :1934-1950