Adjuvant treatment of chronic plaque psoriasis in adults by a herbal combination: Open German trial and review of the literature

被引:2
作者
Wollina, Uwe [1 ]
Franca, Katlein [2 ,3 ,4 ]
Lotti, Torello [4 ]
Tirant, Michael [5 ]
机构
[1] Acad Teaching Hosp Dresden, Dept Dermatol & Venereol, Dresden, Germany
[2] Univ Miami, Miller Sch Med, Dept Dermatol & Cutaneous Surg, Miami, FL 33136 USA
[3] Univ Miami, Miller Sch Med, Dept Psychiat & Behav Sci, Miami, FL 33136 USA
[4] Univ G Marconi, Ctr Ric Multidisciplinare & Rigenerat, Rome, Italy
[5] Psoriasis & Skin Clin, Melbourne, Vic, Australia
关键词
clinical trials; herbal complex; PASI; psoriasis; Soratinex (R); topical treatment; CARE;
D O I
10.1111/dth.12624
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Psoriasis is a chronic inflammatory skin disease affecting up to 6% of the World population. Skin care is the basic approach to restore epidermal barrier function, provide symptomatic relief, and ensure remission-free periods. We performed an open trial using herbal complex Soratinex (R) (also known as Dr Michaels (R)) in adult patients with mild-to-moderate chronic plaque psoriasis without further improvement to previous treatments in the last 6 weeks. The products Cleansing Gel, Scalp & Body Ointment, and Skin Conditioner were applied twice daily for 8 weeks. All patients achieved a Psoriasis Area and Severity Index (PASI) 50 response, 94.4% achieved a PASI 75, 66.7% achieved PASI 90, and 22.2% achieved a PASI 100. In week 8, 94.4% of patients were satisfied or very satisfied with the treatment that was well tolerated. We performed a literature review on published trials in children and adults suffering from psoriasis. Herbal complex Soratinex (R) achieved a PASI 50 or more in about 50-90% of patients. It ensures prolonged relapse-free periods and improves the quality of life. Adverse events are mild and seen in a minority of patients only. In conclusion, herbal complex allows safe and effective self-treatment of patients with psoriasis and improves patient's autonomy.
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页数:5
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