A New Biflavonoid from Schinopsis brasiliensis (Anacardiaceae)

被引：13

作者：

Cardoso, Manuela P. ^{[1
]}

Lima, Luciano S. ^{[2
]}

David, Juceni P. ^{[3
]}

Moreira, Bruno O. ^{[4
]}

Santos, Edlene O. ^{[4
]}

David, Jorge M. ^{[4
]}

Alves, Clayton Q. ^{[5
]}

机构：

[1] Inst Fed Educ Ciencia & Tecnol Bahia, BR-40301015 Salvador, BA, Brazil

[2] Inst Fed Educ Ciencia & Tecnol Bahia, BR-45810000 Porto Seguro, BA, Brazil

[3] Univ Fed Bahia, Fac Farm, BR-40170290 Salvador, BA, Brazil

[4] Univ Fed Bahia, Inst Quim, BR-40170290 Salvador, BA, Brazil

[5] Univ Estadual Feira de Santana, Dept Ciencias Exatas, BR-44036900 Feira De Santana, BA, Brazil

来源：

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY | 2015年 / 26卷 / 07期

关键词：

biflavanone; bichalcone; Schinopsis brasiliensis; Anacardiaceae; ACETYLCHOLINESTERASE;

D O I：

10.5935/0103-5053.20150101

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Phytochemical investigation of the MeOH extract of Schinopsis brasiliensis Engl. stems led to the isolation of the new biflavanone (2R*, 3R*, 2 '' R*, 3 '' R*)-7-hydroxy-4'-methoxy-flavanone-(3 -> 3 '')-3''', 7 ''-dihydroxy-4'''-methoxy-flavanone and 4,2',4'-trihydroxychalcone-(3 -> O -> 4 '')-2''', 4'''-dihydroxychalcone, whereas methyl gallate, gallic acid, (6R, 9R)-megastigma-4-en-3-one-9-O-beta-glucopyranoside, quercetin-3-O-beta-D-xylopyranoside and tricetin-3'-O-beta-D-glucopyranoside were isolated from the MeOH extract of leaves. Their chemical structures were elucidated using spectroscopic methods and comparison with the literature data. Both biflavonoids showed weak inhibition activities of acetyl and butyrylcholinesterase enzymes when compared with eserine.

引用

页码：1527 / 1531

页数：5