In vitro susceptibilities of Chlamydia pneumoniae isolates from German patients and synergistic activity of antibiotic combinations

被引：12
|
作者：
Freidank, HM [1 ]
Losch, P [1 ]
Vögele, H [1 ]
Wiedmann-Al-Ahmad, M [1 ]
机构：
[1] Univ Freiburg, Inst Med Microbiol & Hyg, Dept Bacteriol, D-79104 Freiburg, Germany
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1999年 / 43卷 / 07期
关键词：
D O I：
10.1128/AAC.43.7.1808
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The susceptibilities of six Chlamydia pneumoniae type strains and of six German patient isolates to erythromycin, azithromycin, roxithromycin, clarithromycin, doxycycline, ofloxacin, and rifampin were investigated. MICs and minimal chlamydicidal concentrations were all within the ranges reported previously. Combinations of azithromycin with either ofloxacin, doxycycline, or rifampin, as well as combinations of three antibiotics (rifampin, azithromycin, and ofloxacin or doxycycline), showed synergistic activity against C. pneumoniae.
引用
收藏
页码：1808 / 1810
页数：3
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