Cases of allergic coronary syndrome (Kounis syndrome) : what we should know

被引:2
作者
Akbas, Turkay [1 ]
Kaya, Adnan [2 ]
Altun, Gulsah [3 ]
Esbah, Umit [4 ]
Onmez, Attila [3 ]
机构
[1] Duzce Univ, Fac Med, Dept Internal Med, Div Intens Care, TR-81620 Duzce, Turkey
[2] Duzce Univ, Fac Med, Dept Cardiol, Duzce, Turkey
[3] Duzce Univ, Fac Med, Dept Internal Med, Duzce, Turkey
[4] Duzce Univ, Fac Med, Dept Anesthesia & Reanimat, Duzce, Turkey
关键词
allergic reaction; chest pain; coronary vasospasm; mast cell activation;
D O I
10.18999/nagjms.84.3.664
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Kounis syndrome (KS) is an acute coronary syndrome that occurs with allergic, hypersensitivity, anaphylactic, or anaphylactoid reactions associated with mast cell activation, and entails significant morbidity and mortality risks. We present four cases of acute coronary syndrome developing after insect bites, chemotherapy, and coronary stent implantation. Two patients were lost due to anaphylactic shock-related multiorgan failures and sudden cardiac death. Since a wide range of drugs, foods, environmental conditions, and disease states may be associated with KS, all physicians must be aware of the syndrome.
引用
收藏
页码:664 / 672
页数:9
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