Palladium catalysed Heck and enantioselective allylic substitution reactions using reverse phase silica supports

被引：46
作者：
Anson, MS
Mirza, AR
Tonks, L
Williams, JMJ [1 ]
机构：
[1] Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England
[2] Glaxo Wellcome Res & Dev Ltd, Med Res Ctr, Stevenage SG1 2NY, Herts, England
来源：
TETRAHEDRON LETTERS | 1999年 / 40卷 / 39期
关键词：
D O I：
10.1016/S0040-4039(99)01485-9
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The use of reverse phase controlled-pore glass beads in Heck reactions affords the products with low levels of palladium leaching. Additionally, an enantioselective palladium catalysed allylic substitution reaction has been achieved with high enantiomeric excess and a low level of leaching (C) 1999 Elsevier Science Ltd. All rights reserved.
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收藏
页码：7147 / 7150
页数：4
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