Presence of Cobalt and Chromium Ions in the Seminal Fluid of Young Patients With Metal-on-Metal Total Hip Arthroplasty

被引：12

作者：

Nikolaou, Vassilios S. ^{[1
,2
]}

Petit, Alain ^{[1
,2
]}

Zukor, David J. ^{[1
,2
]}

Papanastasiou, Constantine ^{[1
]}

Huk, Olga L. ^{[1
,2
]}

Antoniou, John ^{[1
,2
]}

机构：

[1] SMBD Jewish Gen Hosp, Lady Davis Inst Med Res, Montreal, PQ H3T 1E2, Canada

[2] McGill Univ, Div Orthopaed Surg, Montreal, PQ H3T 1E2, Canada

来源：

JOURNAL OF ARTHROPLASTY | 2013年 / 28卷 / 01期

关键词：

metal on metal; total hip arthroplasty; metal ions; sperm parameters; fertility; SEMEN PARAMETERS; LIPID-PEROXIDATION; HUMAN-SPERMATOZOA; OXIDATIVE STRESS; HUMAN SPERM; SUBFERTILE POPULATION; MALE-INFERTILITY; FERTILE; QUALITY; BLOOD;

D O I：

10.1016/j.arth.2012.04.019

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

We aimed to investigate the effect of metal ions on the semen of males of child fathering age with metal-on-metal (MM) total hip arthroplasty (THA). Semen was collected form 11 patients with MM THA and 5 control of comparable age. Cobalt and chromiun concentrations were measured in both the seminal plasma and in the blood of patients. Results showed that cobalt level was higher in the seminal plasma of MM THA patients (2.89 mu g/L) compared to control patients (1.12 mu g/L) (P = .011). The ejaculate volume, the sperm density, the total sperm count, the pH, and the percentage of cells with normal morphology were in the range of the World Health Organization criteria for fertile population.

引用

页码：161 / 167

页数：7

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