Acute Heart Failure Syndromes

被引：461

作者：

Gheorghiade, Mihai ^{[1
]}

Pang, Peter S. ^{[2
]}

机构：

[1] Northwestern Univ, Feinberg Sch Med, Div Cardiol, Dept Med, Chicago, IL 60611 USA

[2] Northwestern Univ, Feinberg Sch Med, Dept Emergency Med, Chicago, IL 60611 USA

来源：

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY | 2009年 / 53卷 / 07期

关键词：

heart; failure; decompensated; acute; syndromes; WORSENING RENAL-FUNCTION; INITIATE LIFESAVING TREATMENT; IN-HOSPITAL MORTALITY; FUNCTIONAL MITRAL REGURGITATION; LEFT-VENTRICULAR DYSFUNCTION; CARDIOGENIC PULMONARY-EDEMA; ACUTE MYOCARDIAL-INFARCTION; PRESERVED SYSTOLIC FUNCTION; A(1) RECEPTOR ANTAGONIST; CORONARY-ARTERY-DISEASE;

D O I：

10.1016/j.jacc.2008.10.041

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Heart failure resulting in hospitalization represents a significant and growing health care burden. Heterogeneity characterizes this group in terms of mode of presentation, pathophysiology, and prognosis. The vast majority of patients symptomatically improve during hospitalization; however, their early post-discharge rehospitalization and mortality rates continue to be high. Worsening signs and symptoms, neurohormonal, and renal abnormalities occurring soon after discharge may contribute to these high post-discharge event rates. Currently available assessment modalities combined with recent advances in cardiovascular therapies provide present-day opportunities to improve post-discharge outcomes. Further investigation into pathophysiologic targets and novel approaches to clinical trial design are needed. Improving post-discharge outcomes is the single most important goal in the management of acute heart failure syndromes. (J Am Coll Cardiol 2009; 53: 557-73) (C) 2009 by the American College of Cardiology Foundation

引用

页码：557 / 573

页数：17

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