Intrinsic defaultexecutive coupling of the creative aging brain

被引:22
作者
Adnan, Areeba [1 ]
Beaty, Roger [2 ]
Lam, Jaeger [1 ]
Spreng, R. Nathan [3 ,4 ,5 ,6 ]
Turner, Gary R. [1 ]
机构
[1] York Univ, Dept Psychol, Room 101,Behav Sci Bldg,4700 Keele St, Toronto, ON M3J 1P3, Canada
[2] Harvard Univ, Dept Psychol, 33 Kirkland St, Cambridge, MA 02138 USA
[3] McGill Univ, Lab Brain & Cognit, Montreal Neurol Inst, Montreal, PQ, Canada
[4] McGill Univ, Dept Neurol & Neurosurg, Montreal, PQ, Canada
[5] McGill Univ, Dept Psychol, Montreal, PQ, Canada
[6] McGill Univ, Dept Psychiat, Montreal, PQ, Canada
关键词
creativity; default mode network; aging; executive function; EPISODIC-SPECIFICITY INDUCTION; DIVERGENT THINKING; DEFAULT NETWORK; FUNCTIONAL CONNECTIVITY; OLDER-ADULTS; AGE; OPENNESS; TASK; TIME; MODULATION;
D O I
10.1093/scan/nsz013
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Creativity refers to the ability to generate novel associations and has been linked to better problem-solving and real-world functional abilities. In younger adults, creative cognition has been associated with functional connectivity among brain networks implicated in executive control [fronto-parietal network (FPN) and salience network (SN)] and associative or elaborative processing default network (DN). Here, we investigate whether creativity is associated with the intrinsic network architecture of the brain and how these associations may differ for younger and older adults. Young (mean age: 24.76, n=22) and older (mean age: 70.03, n=44) adults underwent multi-echo functional magnetic resonance image scanning at rest and completed a divergent-thinking task to assess creative cognition outside the scanner. Divergent thinking in older adults, compared to young adults, was associated with functional connectivity between the default and both executive control networks (FPN and SN) as well as more widespread default-executive coupling. Finally, the ventromedial prefrontal cortex appears to be a critical node involved in within- and between-network connectivity associated with creative cognition in older adulthood. Patterns of intrinsic network coupling revealed here suggest a putative neural mechanism underlying a greater role for mnemonic processes in creative cognition in older adulthood.
引用
收藏
页码:291 / 303
页数:13
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