Clinical utility of calprotectin and lactoferrin in patients with inflammatory bowel disease: is there something new from the literature?

被引：11

作者：

Caccaro, Roberta ^{[1
]}

D'Inca, Renata ^{[1
]}

Pathak, Surajit ^{[1
]}

Sturniolo, Giacomo Carlo ^{[1
]}

机构：

[1] Univ Padua, Dept Surg Oncol & Gastroenterol Sci, I-35128 Padua, Italy

来源：

EXPERT REVIEW OF CLINICAL IMMUNOLOGY | 2012年 / 8卷 / 06期

关键词：

calprotectin; disease markers; fecal markers; inflammatory bowel disease; lactoferrin; FECAL CALPROTECTIN; CROHNS-DISEASE; INFLIXIMAB RESPONDERS; ULCERATIVE-COLITIS; SURROGATE MARKERS; RAPID TEST; DIAGNOSIS; CHILDREN; RELAPSE; PREDICTION;

D O I：

10.1586/ECI.12.50

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The identification of noninvasive biomarkers is still one of the major issue for gastroenterologists dealing with inflammatory bowel disease patients, due to the chronicity of these conditions and the early onset of symptoms in the majority of cases. Research attention has focused mainly on fecal proteins, especially calprotectin and lactoferrin, and most of the published data are reassuring about their applicability in the diagnosis and monitoring of these patients. However, there are still pending questions regarding the reliability of fecal proteins especially in the era of mucosal healing and biologics.

引用

页码：579 / 585

页数：7

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