Exercise-induced ventricular tachycardia in a case with hypertrophic cardiomyopathy taking cibenzoline

被引：0

作者：

Shiohira, Shinya ^{[1
]}

Kawabata, Mihoko ^{[1
,2
]}

Goya, Masahiko ^{[1
]}

Maeda, Shingo ^{[2
]}

Sasano, Tetsuo ^{[1
]}

Hirao, Kenzo ^{[2
]}

机构：

[1] Tokyo Med & Dent Univ, Dept Cardiovasc Med, Tokyo, Japan

[2] AOI Universal Hosp, Arrhythmia Adv Therapy Ctr, Kawasaki, Kanagawa, Japan

来源：

ANNALS OF NONINVASIVE ELECTROCARDIOLOGY | 2021年 / 26卷 / 01期

关键词：

hypertrophic cardiomyopathy; proarrhythmia; QRS duration; sodium channel blocker; use-dependent; ventricular tachycardia;

D O I：

10.1111/anec.12789

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report a 17-year-old woman with hypertrophic cardiomyopathy (HCM) successfully resuscitated from ventricular fibrillation while taking cibenzoline. During exercise-stress testing before implanting an implantable cardioverter-defibrillator, ventricular tachycardia was induced and thought to be a proarrhythmia due to the use-dependent effect of the Na channel blockade with cibenzoline. In patients with arrhythmogenic substrates such as HCM, it is critical to pay attention to the proarrhythmic effects of class I antiarrhythmic drugs while increasing heart rate.

引用

页数：4

共 4 条

[1]

[Anonymous], 1998, AM J CARDIOL

[2]

Gersh BJ, 2011, CIRCULATION, V124, P2761, DOI 10.1161/CIR.0b013e318223e230

[3] Antiarrhythmic drug, cibenzoline, can directly improve the left ventricular diastolic function in patients with hypertrophic cardiomyopathy [J].

Hamada, M ;

Shigematsu, Y ;

Hara, Y ;

Suzuki, M ;

Ohtsuka, T ;

Hiasa, G ;

Ogimoto, A ;

Saeki, H ;

Suzuki, J ;

Hiwada, K .

JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION, 2001, 65 (06) :531-538

[4] AMPLIFICATION OF FLECAINIDE-INDUCED VENTRICULAR CONDUCTION SLOWING BY EXERCISE - A POTENTIALLY SIGNIFICANT CLINICAL CONSEQUENCE OF USE-DEPENDENT SODIUM-CHANNEL BLOCKADE [J].

RANGER, S ;

TALAJIC, M ;

LEMERY, R ;

ROY, D ;

NATTEL, S .

CIRCULATION, 1989, 79 (05) :1000-1006

← 1 →