Right heart failure in the intensive care unit

被引:12
作者
Greyson, Clifford R. [1 ,2 ]
机构
[1] Dept Vet Affairs Med Ctr, Denver, CO USA
[2] Univ Colorado, Sch Med, Denver, CO USA
关键词
cor pulmonale; pulmonary hypertension; right ventricle; ventricular assist device; RIGHT-VENTRICULAR FAILURE; PULMONARY ARTERIAL-HYPERTENSION; RESPIRATORY-DISTRESS-SYNDROME; JUGULAR VENOUS DISTENSION; PRESSURE-OVERLOAD; ASSIST DEVICE; ATRIAL SEPTOSTOMY; SYSTOLIC FUNCTION; DYSFUNCTION; FLOW;
D O I
10.1097/MCC.0b013e3283577070
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Purpose of review This review summarizes the approach to and recent developments in the evaluation and treatment of acute right heart failure in the ICU. Right heart failure, defined as failure of the right ventricle to provide sufficient blood flow through the pulmonary circulation at normal central venous pressure, is a common problem caused by a combination of increased right-ventricular afterload and right-ventricular contractile dysfunction. Recent findings Management of acute right heart failure continues to be challenging because of insufficient understanding of its pathophysiology, a lack of guidelines, and few available tools. Recent research has contributed to an improved understanding of its mechanisms, helping to guide therapy and suggest future options. Right-ventricular assist devices are emerging as a promising approach to treatment when optimization of hemodynamics and conventional medical therapy fail. Summary Right heart failure causes venous congestion and systemic hypoperfusion. Once right heart failure is identified, the primary goal is to alleviate any reversible cause of excessive load or right-ventricular contractile failure. When the underlying abnormalities cannot be alleviated, trials of diuretic, vasodilator, or inotropic therapy may be required. Invasive monitoring helps guide therapy. Medically refractory right heart failure may potentially be treated with right-ventricular assist devices.
引用
收藏
页码:424 / 431
页数:8
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