Invasive Fungal Rhinosinusitis in the Era of COVID-19: Is It an Emerging Association?

被引:0
作者
Chatzisouleiman, Ipek [1 ]
Lialiaris, Stergios [1 ]
Zisoglou, Maria [1 ]
Katsilidou, Melina [1 ]
Katotomichelakis, Michail [1 ]
机构
[1] Democritus Univ Thrace, Gen Univ Hosp Alexandroupolis, Otolaryngol Head & Neck Surg, Alexandroupolis, Greece
关键词
fungal; aspergillus; immunosufficiency; rhinosinusitis; invasive; covid-19;
D O I
10.7759/cureus.27222
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Invasive fungal rhinosinusitis (IFRS) typically affects immunocompromised patients. The coronavirus disease 2019 (COVID-19) pandemic may be associated with rare opportunistic fungal infections, probably as a result of immune dysregulation. The COVID-19 infection is characterized by low levels of CD4+T and CD8+T cells which could increase the risk of co-infections from Mucor or Aspergillus species. An invasive fungal infection should be suspected in patients who have recently recovered from COVID-19 pneumonia and present with acute destructive rhinosinusitis. There are few cases of IFRS reported in Europe during the pandemic of COVID-19. We describe the case of a 67-year-old patient with diabetes who received corticosteroids during the treatment for COVID-19 infection and was readmitted a few days later for radiologically and clinically suggested IFRS. Aspergillus niger was identified, and the patient received pharmacological and surgical treatment.
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页数:4
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