Paerucumarin, a new metabolite produced by the pvc gene cluster from Pseudomonas aeruginosa

被引：48

作者：

Clarke-Pearson, Michael F. ^{[1
]}

Brady, Sean F. ^{[1
]}

机构：

[1] Rockefeller Univ, Lab Genetically Encoded Small Mol, New York, NY 10065 USA

来源：

JOURNAL OF BACTERIOLOGY | 2008年 / 190卷 / 20期

关键词：

D O I：

10.1128/JB.00801-08

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The pvc gene cluster from Pseudomonas aeruginosa has been linked to the biosynthesis of both the pyoverdine chromophore and pseudoverdine. Our reinvestigation of the role this gene cluster plays in P. aeruginosa secondary metabolite biosynthesis shows that its major product is actually paerucumarin, a novel isonitrile functionalized cumarin.

引用

页码：6927 / 6930

页数：4

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